泛发性发疹性组织细胞瘤1例  

A Case of Generalized Eruptive Histiocytoma

作　　者：董田田 范婷婷 王申卉 张钰[1] 陈溪[1] 高微[1] 夏建新[1] DONG Tiantian;FAN Tingting;WANG Shenhui;ZHANG Yu;CHEN Xi;GAO Wei;XIA Jianxin(Department of Dermatology,the Second Hospital of Jilin University,Changchun 130041,China)

机构地区：[1]吉林大学第二医院皮肤科,吉林长春130041

出　　处：《中国皮肤性病学杂志》2019年第1期70-72,共3页The Chinese Journal of Dermatovenereology

摘　　要：患者女,53岁。躯干、四肢对称性大小不等红棕色丘疹20余天,无疼痛及瘙痒。皮损组织病理示:真皮浅中层血管周围及胶原纤维间组织细胞密集浸润,间有少量淋巴细胞浸润。免疫组织化学染色示:CD68(+)、Ki-67(阳性率<5%)、S100(-)、CD1a(-)。诊断:泛发性发疹性组织细胞瘤(GEH)。给予雷公藤口服,外用丙酸氟替卡松治疗2个月后,皮损完全消退,遗留少许色素沉着斑。A 53-year-old female presented with reddish-brown papules on the trunk and extremities with no adverse complaint for more than 20days.Histopathology revealed dense histiocyte-like cells infiltration in perivascular area and between the collagen fibers throughout the superficial dermis,along"with a few lymphocytes infiltration.The histiocyte-like infiltrates were positive for CD68 and less than 5% expression of Ki-67,but negative for CDla and S100.According to the above findings,the patient was diagnosed as generalized eruptive histiocytoma (GEH).Treatment with oral tripterygium glucosides and topical fluticasone propionate ointment for 2 months resulted in completely remission,leaving only a little pigmentation.

关 键 词：组织细胞瘤 泛发性 发疹性 

分 类 号：R739.5[医药卫生—肿瘤]