儿童重症化脓性脑膜炎的诊断与治疗  

Diagnosis and treatment of childhood severe purulent meningitis

作　　者：宋晓洁[1] 蒋莉[1] Song Xiaojie;Jiang Li(Department of Neurology,Children's Hospital of Chongqing Medical University,Ministry of Education Key Laboratory of Child Development and Disorders,Chongqing 400014,China)

机构地区：[1]重庆医科大学附属儿童医院神经内科,儿童发育疾病研究教育部重点实验室,儿童发育重大疾病国家国际科技合作基地,儿科学重庆市重点实验室,400014

出　　处：《中国小儿急救医学》2018年第12期888-892,共5页Chinese Pediatric Emergency Medicine

摘　　要：重症化脓性脑膜炎起病急骤、迅速进展,病死率和致残率高,其发生与患儿年幼,免疫功能与屏障机能发育不成熟,或存在免疫缺陷、异常通道有关;也与致病菌的毒力和对抗生素的耐药性有关。早期识别重症化脓性脑膜炎的临床特征和致病相关因素,尽早加强抗生素治疗,积极进行综合对症支持治疗,监测和处理并发症,对改善重症化脓性脑膜炎患儿的预后具有重要意义。Severe purulent meningitis (PM)is urgent suddenly and progresses quickly with high mortality and disabled rate.The occurrence of severe PM is associated with young children,immature immune function and barrier function,immune deficiency,or anatomic defects.The virulence of pathogenic and resistance to antibiotics are also related to severe PM.It will be significant for improving prognosis to identify and control pathogenic factors,early diagnosis,to strengthen antibiotic treatment as early as possible,to carry out appropriate symptomatic and supportive treatment,to monitor and manage complications.

关 键 词：儿童 重症化脓性脑膜炎 预后 危险因素 

分 类 号：R742[医药卫生—神经病学与精神病学]