相干光断层扫描血管成像辅助青光眼诊断与评估  

The application of optical coherence tomography angiography for diagnosis and evaluation of glaucoma

作　　者：曲乐 杨瑾[1] QU Yue;YANG Jin(Clinical College of Ophthalmology of Tianjin Medical University, Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin 300020, China)

机构地区：[1]天津医科大学眼科临床学院、天津市眼科医院、眼科学与视觉科学天津市重点实验室、天津市眼科研究所,300020

出　　处：《国际眼科纵览》2018年第6期418-422,共5页International Review of Ophthalmology

摘　　要：相干光断层扫描血管成像(optical coherence tomography angiography,OCTA)通过提供可视化的血管三维立体结构,量化视网膜、脉络膜血流,同时获取相应的结构参数,实现对眼后节的无创性评估。青光眼患者视网膜血流明显低于正常人,而OCTA对视盘及黄斑区血流的定量、定性分析与青光眼患者的结构及功能的改变有强相关性。利用OCTA检测患者异常血流状态,与临床表现及青光眼其他检查技术结合进行分析,可为青光眼的早期诊断及病情评估提供更可靠的依据。(国际眼科纵览,2018,42:418-422)Optical coherence tomography angiography (OCTA) is a non-invasive imaging technology that can be used to assess the posterior segment of the eye by providing three-dimensional image of the vessels, quantifying the retinal and choroidal blood flow, and obtaining corresponding structural parameters. The retinal vessel density(VD) of glaucoma was significantly lower than that of normal control. Quantitative analysis of optic disc and macular VD by OCTA was strongly correlated with the changes in the structure and function of glaucoma. Therefore, detecting abnormal blood flow in glaucoma using OCTA combined with clinical manifestations and other examination techniques can provide a more reliable early diagnosis and disease assessment of glaucoma. (Int Rev Ophthalmol,2018,42:418-422)

关 键 词：相干光断层扫描血管成像 青光眼 血管密度 

分 类 号：R779.63[医药卫生—眼科]