玫瑰茄提取物对小鼠醉酒预防作用的研究  

Preventive Effect of Hibiscus Sabdariffa Extract on Temulentia Mice

作　　者：危青霞 郑洲 沈锦煌 李佳怡 张桂华 李鹏[1] WEI Qing-xia;ZHENG Zhou;SHEN Jin-huang;LI Jia-yi;ZHANG Gui-hua;LI Peng(School of Pharmacy,Fujian Medical University,Fuzhou 350122,China)

机构地区：[1]福建医科大学药学院,福州350122

出　　处：《海峡药学》2018年第12期26-28,共3页Strait Pharmaceutical Journal

基　　金：福建医科大学大学生创新创业训练计划项目(C17098);福建省科技创新平台项目(2018Y001)

摘　　要：目的探讨玫瑰茄不同提取物对小鼠醉酒的预防作用。方法采用预防醉酒实验,观察玫瑰茄不同提取物对小鼠醉酒的影响。结果玫瑰茄水提醇沉上清部分能明显缩短小鼠平均醉酒时长,与对照组相比,有显著性差异(P<0.05)。结论玫瑰茄水提醇沉上清部分对小鼠醉酒具有较显著的预防作用。OBJECTIVE To explore the preventive effect of the different extracts of Hibiscus Sabdariffa on temulentia mice.METHODS Anti-inebriation of the different extracts of Hibiscus Sabdariffa was observed by means of temulentia prevention experiment.RESULTS Water extraction and alcohol precipitation supernatant group significantly shorten the drunken sleeping time,compared with the control group(P<0.05).CONCLUSION Water extraction and alcohol precipitation supernatant group of Hibiscus Sabdariffa has significant preventive effects on temulentia mice.

关 键 词：玫瑰茄 醉酒 小鼠 预防 

分 类 号：R965[医药卫生—药理学]