碘介导下通过氧化性C—O键形成合成异噁唑类化合物（英文）  

I_2-Mediated Oxidative C—O Bond Formation for the Synthesis of Isoxazoles

作　　者：侯姣 张新婷 于文全[1] 常俊标[1] Hou Jiao;Zhang Xinting;Yu Wenquan;Chang Junbiao(College of Chemistry and Molecular Engineering,Zhengzhou University,Zhengzhou 450001)

机构地区：[1]郑州大学化学与分子工程学院,郑州450001

出　　处：《有机化学》2018年第12期3236-3241,共6页Chinese Journal of Organic Chemistry

基　　金：supported by the National Natural Science Foundation of China(Nos.81773570,81330075);the Outstanding Young Talent Research Fund of Zhengzhou University(No.1521316004)~~

摘　　要：通过碘介导的氧化性C—O键形成反应由易得的α,β-不饱和肟合成了一系列单、双和三取代(芳基、烷基和/或烯基)的异噁唑类化合物.该合成方法具有不使用过渡金属、操作简单、反应条件温和、反应时间短,以及底物适用范围广等优点.A variety of mono-, di-, and tri-substituted(aryl, alkyl, and/or alkenyl) isoxazoles were synthesized from readily accessible α,β-unsaturated oximes via I2-mediated oxidative C-O bond formation. The features of this synthetic approach include no use of transition metals, simple operation, mild reaction conditions, short reaction time, and broad substrate scope.

关 键 词：异噁唑 碘 α β-不饱和肟 C-O键形成 

分 类 号：O626[理学—有机化学]