宫颈癌外照射Pinnacle与Monaco系统容积调强物理方案的比较分析及方案质量评估模型的创建  

Two Physical Schemes of External Radiation for Cervical Cancer and the Establishment of Scheme Quality Evaluation Model: A Comparison of Pinnacle and Monaco Treatment Planning Systems

作　　者：柏晗 吴星娆 陈飞虎 刘旭红 鄢佳文 Bai Han;Wu Xingrao;Chen Feihu;Liu Xuhong;Yan Jiawen(Yunnan Cancer Hospital &The Third Affiliated Hospital of Kunming Medical University &Yunnan Cancer Center,Kunming 650118,Yunnan,China)

机构地区：[1]云南省肿瘤医院.昆明医科大学第三附属医院.云南省癌症中心,昆明650118

出　　处：《肿瘤预防与治疗》2019年第1期61-66,共6页Journal of Cancer Control And Treatment

基　　金：云南省应用基础研究(编号:2017FE468-221)~~

摘　　要：目的:创建新的物理方案质量评估模型,弥补传统评估物理方案质量方法的不足。方法:采用Pinnacle和Monaco TPS分别为12例宫颈癌患者设计外照射物理方案(pV-Plan,mV-Plan),采用传统的评估方法对2种TPS设计的放疗物理方案进行比较和评估,深入探讨传统方法的不足和可能存在的风险,在此基础上创建新的物理方案质量评估模型f(TCP～NTCP),并采用文献中报道的f(EUD)模型检验其有效性。结果:传统的评估方法不能比较出pV-Plan,mV-Plan两种物理方案在整体上的优劣;采用f(TCP～NTCP)模型可以发现两种物理方案在整体上的优劣,且结果与f(EUD)比较的结果一致。结论:传统评估物理方案质量的方法存在不足,f(TCP～NTCP)模型可以作为新的物理方案质量评估模型,辅助评估物理方案质量。Objective:To create a new model for evaluating the quality of physical scheme of the extemal radiation for cervical cancer,and compensate the shortcomings of traditional physical scheme quality evaluation models.Methods:Pinnacle and Monaco treatment planning systems (TPS)were adopted to design external radiation physical scheme (pV-Plan,mV-Plan) for 12 patients with cervical cancer,respectively.We then evaluated the two plans with traditional evaluation methods,and discussed the shortcomings and possible risks of doing this.On the basis of that,we created a new model,f(TCP^NTCP),for evaluating the quality of physical scheme,and tested its validity against the f(EUD)model reported in an article.Results: Traditional evaluation methods could not tell the difference between pV-Plan or mV-Plan.Instead,thef(TCP^NTCP)model could.Those results were in accord with the results from f(EUD)model.Conclusion:The traditional method for evalua-ring the quality of physical scheme is insufficient,f(TCP^NTCP)model can be used as a new and adjuvant model for evaluating the quality of physical scheme.

关 键 词：宫颈癌 物理方案质量 评估模型 

分 类 号：R737.34[医药卫生—肿瘤]