HAb18G表达与非小细胞肺癌的病理特征、转移及预后的关系  

Relationship between HAb18G expression and pathological features,metastasis and prognosis of non-small cell lung cancer

作　　者：崔丽萍[1] 朱佳荣[2] 王磊[3] Cui Liping;ZHU Jiarong;WANG Lei(Department General Medical,General Hospital of Ningxia Medical University,Yinchuan 750004,China;Department of Respiractory Medical and Cnitrcal lumess of Ningxia Medical University,Yinehuan 750004,China;Resipiratory Medicine Department,The Second Peoples Hospital of Shizuishan ,Dawakou 753000,China)

机构地区：[1]宁夏医科大学总医院全科医学科,宁夏银川750004 [2]宁夏医科大学总医院呼吸与危重病医学科,宁夏银川750004 [3]宁夏石嘴山市第二人民医院呼吸内科,宁夏石嘴山753000

出　　处：《宁夏医学杂志》2018年第12期1075-1077,共3页Ningxia Medical Journal

摘　　要：目的探讨(HAb18G)表达与非小细胞肺癌的病理特征、转移及预后的关系。方法采用回顾性方法对86例非小细胞肺癌患者的临床资料进行分析,用免疫组织化学SP法检测HAb18G表达水平,分析HAb18G表达与非小细胞肺癌的关系。结果鳞癌、大细胞癌、腺癌的HAb18G表达水平经统计学分析,差异无统计学意义(P> 0. 05)。HAb18G表达水平与肿瘤最大直径、分化程度、淋巴结转移、TNM分期相关,其差异有统计学意义(P <0. 05)。结论非小细胞肺癌患者中HAb18G表达与其病理特征、转移及预后有一定关系,可作为疾病发生发展的重要参考指标。Objective To explore the relationship between hepatocyte membrane surface related antigen( HAb18 G) expression and pathological features,metastasis and prognosis of non-small cell lung cancer. Methods A retrospective analysis was conducted,the clinical data of 86 patients with non-small cell lung cancer treated. The expression level of HAb18 G was detected by immunohistochemical SP method,and the relationship between HAb18 G expression and non small cell lung cancer was analyzed. Results The expression level of HAb18 G in squamous cell carcinoma,large cell carcinoma and adenocarcinoma was statistically analyzed,and there was no significant difference( P > 0. 05). The level of HAb18 G expression was correlated with maximum diameter of tumor,degree of differentiation,lymph node metastasis and TNM staging,and the difference was statistically significant( P < 0. 05). Conclusion The expression of HAb18 G in non-small cell lung cancer patients is related to their pathological features,metastasis and prognosis. It can be used as an important reference index for the occurrence and development of non-small cell lung cancer.

关 键 词：非小细胞肺癌 肝细胞膜表面相关抗原 病理特征 转移 预后 

分 类 号：R734.2[医药卫生—肿瘤]