胰高血糖素瘤综合征1例  

A Case of Glucagonoma Syndrome

作　　者：聂樱丽 张亚敏[1] 曾敬思[1] 黄长征[1] 陶娟 涂亚庭[1] NIE Yingli;ZHANG Yamin;ZENG Jingsi;HUANG Changzheng;TAO Juan;TU Yating(Department of Dermatology,Affiliated Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China)

机构地区：[1]华中科技大学同济医学院附属协和医院皮肤科,湖北武汉430022

出　　处：《中国皮肤性病学杂志》2019年第2期195-197,共3页The Chinese Journal of Dermatovenereology

摘　　要：患者男,44岁。躯干、四肢出现红斑、糜烂伴痒4个月,加重1个月。皮损组织病理示:角化过度伴融合性角化不全,棘层增生肥厚,皮突下延增宽,可见部分棘层上部细胞胞浆空泡化和苍白,真皮浅层淋巴组织细胞浸润。诊断:胰高血糖素瘤综合征。A 44-year-old male presented with recurrent erythema and erosion accompanied by itchiness for four months,which were aggravated for one month.The histopathologic examination showed epidermal hyperkeratosis with confluent parakeratosis,acanthosis,elongation of the rete ridges,partial vacuolated and pale staining cells and a few necrotic cells in the upper part of the epidermis,and mild lymphohistiocytic infiltration in the superficial dermis.A diagnosis of glucagonoma syndrome was established.

关 键 词：胰高血糖素瘤综合征 坏死松解性游走性红斑 

分 类 号：R735.9[医药卫生—肿瘤]