Recent approaches to His-Purkinje system pacing  

作　　者：Li-Ting Cheng Jun-Meng Zhang Ze-Feng Wang Hui-Kuan Gao Yong-Quan WU 

机构地区：[1]Department of Cardiology,Beijing Anzhen Hospital,Capital Medical University,Beijing 100029,China [2]Department of Cardiology,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China

出　　处：《Chinese Medical Journal》2019年第2期190-196,共7页中华医学杂志（英文版）

基　　金：a grant from the National Natural Science Foundation of Ghina (No.81570220).

摘　　要：Objective:Physiologic cardiac pacing is a novel technique which has been largely popularized in recent decades.His bundle pacing (HBP) has been long considered the most physiologic pacing method;however, with the widespread implementation of this method, its disadvantages have become apparent.In this context, left bundle branch pacing (LBBP)-directly engaged in the His-Purkinje system-has been foreseen as the best pacing method to mimic physiologic activation patterns.This review aimed to summarize recent approaches to physiologic cardiac pacing.Data sources:This review included fully peer reviewed publications up to July 2018, found in the PubMed database using the keywords "His bundle branch pacing," "right ventricular pacing," and "physiologic pacing." Study selection:All selected articles were in English, with no restriction on study design.Results:The HBP has been studied worldwide, and is currently considered the most physiologic pacing method.However, it has disadvantages, such as high pacing threshold, unsatisfactory sensing and long procedure times, among others.Although LBBP is theoretically superior to HBP, the clinical relevance of this difference remains under debate, as few large randomized clinical trials with LBBP have been published.Conclusions:Although HBP indeed appears to be the most physiologic pacing method, it has certain shortcomings, such as high pacing threshold, difficult implantation due to specific anatomic features, and others.Further studies are required to clarify the clinical significance of LBBP.

关 键 词：His-Purkinje PACING His BUNDLE PACING Cardiac RESYNCHRONIZATION therapy Left BUNDLE branch PACING 

分 类 号：R[医药卫生]