维生素D、自噬与口腔疾病  

Vitamin D,autophagy and oral diseases

作　　者：王健[1] 吴倩[1] 胡新月 杨雪[1] 牛丽 唐晓琳[1] WANG Jian;WU Qian;HU Xin-yue;YANG Xue;NIU Li;TANG Xiao-lin(Department of Periodontology ,School and Hospital of Stomatology ,China Medical University,Shenyang 110002,China)

机构地区：[1]中国医科大学口腔医学院.附属口腔医院牙周病科,辽宁沈阳110002

出　　处：《中国实用口腔科杂志》2018年第12期754-759,共6页Chinese Journal of Practical Stomatology

基　　金：国家自然科学基金(81670999)

摘　　要：自噬在真核生物进化过程中起着重要作用。在自噬过程中,细胞可通过降解自身的非必需成分来提供营养和能量,从而实现胞内物质转化和应对短暂的生存压力。自噬与多种口腔疾病关系密切。维生素D是一种重要的自噬激活因子,积极参与调节免疫和炎症反应。文章对维生素D、自噬与口腔疾病的关系做一综述。Autophagy plays an important role in the evolution of eukaryotes. In the process of autophagy,the cell can provide nutrients and energy through the degradation of non-essential components of the cell to achieve the turnover of intracellular materials and to cope with transient stress. Autophagy is associated with a variety of oral diseases. Vitamin D can promote autophagy and actively participats in the regulation of immune and inflammatory responses. This article reviews the relationship among vitamin D,autophagy,and oral diseases.

关 键 词：维生素D 自噬 口腔疾病 

分 类 号：R78[医药卫生—口腔医学]