Palmitoylation stabilizes PD-L1 to promote breast tumor growth  

作　　者：Yi Yang Jung-Mao Hsu Linlin Sun Li-Chuan Chan Chia-Wei Li Jennifer L. Hsu Yongkun Wei Weiya Xia Junwei Hou Yufan Qiu Mien-Chie Hung 

机构地区：[1]Department of Molecular and Cellular Oncology,The University of Texas MD Anderson Cancer Center,Houston,TX 77030,USA [2]Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment,Lung Cancer Institute,Tianjin Medical University General Hospital,Tianjin 30052,China [3]Graduate School of Biomedical Sciences,The University of Texas Health Science Center at Houston,Houston,TX 77030,USA [4]The 3rd Department of Breast Cancer,China Tianjin Breast Cancer Prevention,Treatment and Research Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center of Cancer,Tianjin 300060,China

出　　处：《Cell Research》2019年第1期83-86,共4页细胞研究（英文版）

摘　　要：Dear Editor,PD-L1 is a well-known transmembrane protein, which is highly expressed on many types of cancer cells. By binding to its receptor PD-1 on T cells, PD-L1 significantly inhibits T cells activation and activity, and thus plays a pivotal role in driving the escape of tumor cells from immune surveillance.^1.

关 键 词：well-known TRANSMEMBRANE protein receptor PD-1 

分 类 号：Q[生物学]