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TRANSMEMBRANE: 作品数：139被引量：311H指数：10; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：唐标周勇邬林泉高伟李倩倩更多>>; 相关机构：北京化工大学苏州大学南京农业大学湖南中医药大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金重庆市自然科学基金更多>>

Smad transcription factors as mediators of 7 transmembrane G protein-coupled receptor signalling: 《Acta Pharmacologica Sinica》2025年第4期795-804,共10页Zheng-Jie Chia Hirushi Kumarapperuma Ruizhi Zhang Peter J.Little Danielle Kamato; supported by a Future Leader Fellowship(106605)from the National Heart Foundation of Australia;HK and ZJC are supported by the Research Training Scholarship from the University of Queensland.; The Smad transcription factors are well known for their role at the core of transforming growth factor-β(TGF-β)signalling.However,recent evidence shows that the Smad transcription factors play a vital role downstrea...; 关键词：transforming growth factor-beta receptor SMAD transactivation dependent GPCR signalling Akt phospho-Smad

TMED3 promotes prostate cancer via FOXO1a and FOXO3a phosphorylation: 《Oncology Research》2025年第1期161-169,共9页XIUWANG WEI JIANBO LIANG HUANWEN HUANG DAMING YANG XINXIN WANG XIUJIA WANG CHANGSHENG CHEN KAIQIANG LI TAISEN PANG BIN HU FENGNING WU; supported by Guangxi Medical and Health Appropriate Technology Development and Promotion Application Project(S2022022).; Background:Transmembrane emp24 trafficking protein 3(TMED3)is associated with the development of several tumors;however,whether TMED3 regulates the progression of prostate cancer remains unclear.Materials and Methods:...; 关键词：Prostate cancer Transmembrane emp24 trafficking protein 3(TMED3) forkhead box O transcription factor(FOXO) Proliferation Apoptosis

Key amino acid residues govern the substrate selectivity of the transporter Xltr1p from Trichoderma reesei for glucose, mannose, and galactose: 《Engineering Microbiology》2024年第4期1-11,共11页Wei Ma Shiyu Yuan Zixian Wang Kangle Niu Fengyi Li Lulu Liu Lijuan Han Xu Fang; This work was supported by National Key R&D Program of China(No.2018YFA0901700);National Natural Science Foundation of China(No.32271526).; This research identified four amino acid residues(Leu174,Asn297,Tyr301,and Gln291)that contribute to sub-strate recognition by the high-affinity glucose transporter Xltr1p from Trichoderma reesei.Potential hotspots af...; 关键词：Hexose transporter GLUCOSE GALACTOSE MANNOSE Transmembrane α-helix 7 Sugar transport Computer-aided screening

Transmembrane serine protease 4 expression in the prognosis of radical resection for biliary tract cancer: 《World Journal of Gastrointestinal Surgery》2024年第8期2555-2564,共10页Yoshiyuki Shibata Takeshi Sudo Sho Tazuma Naoki Tanimine Takashi Onoe Yosuke Shimizu Atsushi Yamaguchi Kazuya Kuraoka Shinya Takahashi Hirotaka Tashiro; BACKGROUND Recent advancements in biliary tract cancer(BTC)treatment have expanded beyond surgery to include adjuvant therapy,yet the prognosis remains poor.Identifying prognostic biomarkers could enhance the assessme...; 关键词：Biliary tract cancer BIOMARKER PROGNOSIS Radical resection Transmembrane serine protease 4

Six transmembrane epithelial antigens of the prostate to illustrate inflammatory response in gastrointestinal cancers: 《World Journal of Clinical Oncology》2024年第8期961-964,共4页Yi-Han Wu Lian-Xiang Luo; Gastrointestinal cancer(GIC)is a common and widespread form of tumor,with colonoscopy and upper gastrointestinal endoscopy available to detect relevant precancerous polyps and lesions.However,many patients are already...; 关键词：Six transmembrane epithelial antigens of the prostate Gastrointestinal cancer Inflammation Gastric cancer Colorectal cancer Hepatocellular carcinoma

Potential role of transmembrane 9 superfamily member 1 as a biomarker in urothelial cancer: 《World Journal of Clinical Oncology》2024年第8期965-967,共3页Alvaro Pinto Abrahams Ocanto Felipe Couñago; Bladder cancer is a urological tumor with high rates of recurrence despite recent advances in novel therapies.Many proteins involved in the molecular mechanisms are currently an enigma,especially the transmembrane 9 s...; 关键词：Bladder cancer Transmembrane 9 superfamily member 1 BIOMARKER Urothelial cancer PROTEIN

Single transmembrane GPCR modulating proteins:neither single nor simple: 《Protein & Cell》2024年第6期395-402,共8页Meng Wang Jianjun Lyu Chao Zhang; supported by the National Natural Science Foundation of China(Grant No.32271165);Shanghai Clinical Research Center of Plastic and Reconstructive Surgery supported by the Science and Technology Commission of Shanghai Municipality(Grant No.22MC1940300);the Innovative Research Team of High-level Local Universities in Shanghai(Grant No.SHSMU-ZDCX20210400);the Key Laboratory Program of the Education Commission of Shanghai Municipality(No.ZDSYS14005);China Postdoctoral Science Foundation(Grant No.2022M722127).; The discovery of G-protein coupled receptor(GPCR)accessory proteins has fundamentally redefined the pharmacological concept of GPCR signaling,demonstrating a more complex molecular basis for receptor specificity on th...; 关键词：specificity GPCR NEITHER

A novel semi-dominant allele of the transmembrane NAC transcription factor ZmNTL2 reduces the size of multiple maize organs被引量：1: 《The Crop Journal》2024年第3期676-687,共12页Chuan Li Yun Bai Yuwei Hou Siyu Wang Yue Xin Tao Yu Jing Wang Xiaowei Liu Hongyang Yi Chao Xia Hai Lan Moju Cao; supported by The National Key Research and Development Program of China(2022YFD1200704--3);Crop Varietal Improvement and Insect Pests Control by Nuclear Radiation,Platform for Mutation Breeding by Radiation of Sichuan(2021YFYZ0011);Natural Science Foundation of Sichuan Province(2022NSFSC1635);Applied Basic Research Programs of Sichuan Provincial Science and Technology Department(2020YJ0249)。; Maize plant architecture influences planting density and,in turn,grain yield.Most of the plant architecture-related traits can be described as organ size.We describe a miniature maize mutant,Tiny plant 4(Tip4),which e...; 关键词：Organ size c-ray mutagenesis Membrane-bound NAC TF Hormone homeostasis MAIZE

Understanding the role of transmembrane 9 superfamily member 1 in bladder cancer pathogenesis: 《World Journal of Clinical Oncology》2024年第4期468-471,共4页Venkata Krishna Vamsi Gade Budhi Singh Yadav; In this editorial we comment on the article by Wei et al,published in the recent issue of the World Journal of Clinical Oncology.The authors investigated the role of Transmembrane 9 superfamily member 1(TM9SF1)protein...; 关键词：Urinary bladder cancer Transmembrane 9 superfamily member 1 gene cell line Lentiviral vectors Wound healing assay ONCOGENE Proliferation Migration

Inflammatory response in gastrointestinal cancers:Overview of six transmembrane epithelial antigens of the prostate in pathophysiology and clinical implications被引量：1: 《World Journal of Clinical Oncology》2024年第1期9-22,共14页Ze-Xuan Fang Wen-Jia Chen Zheng Wu Yan-Yu Hou Yang-Zheng Lan Hua-Tao Wu Jing Liu; the National Natural Science Foundation of China,No.82273457;the Natural Science Foundation of Guangdong Province,No.2021A1515012180,2023A1515012762 and No.2019A1515010962;Special Grant for Key Area Programs of Guangdong Department of Education,No.2021ZDZX2040;Science and Technology Special Project of Guangdong Province,No.210715216902829.; Chronic inflammation is known to increase the risk of gastrointestinal cancers(GICs),the common solid tumors worldwide.Precancerous lesions,such as chronic atrophic inflammation and ulcers,are related to inflammatory ...; 关键词：Six transmembrane epithelial antigens of the prostate Gastrointestinal cancer Inflammation

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