MANNOSE

作品数：49被引量：92H指数：5
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相关领域：医药卫生更多>>
相关作者：成瑜赵曦刘丽艳刘昭军李铁更多>>
相关机构：爱知医科大学黑龙江省农业科学院深圳市宝安区妇幼保健院合肥工业大学更多>>
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D‑mannose alleviates intervertebral disc degeneration through glutamine metabolism
《Military Medical Research》2025年第3期313-338,共26页Zheng-Lin Dong Xin Jiao Zeng-Guang Wang Kai Yuan Yi-Qi Yang Yao Wang Yun-Tao Li Tian-Chang Wang Tian-You Kan Jian Wang Hai-Rong Tao 
supported by the National Key Research and Development Program of China(2020YFB1711505).
Background:Intervertebral disc degeneration(IVDD)is a multifaceted condition characterized by heterogeneity,wherein the balance between catabolism and anabolism in the extracellular matrix of nucleus pulposus(NP)cells...
关键词：D-MANNOSE Intervertebral disc degeneration(IVDD) Thioredoxin-interacting protein(TXNIP) GLUTAMINE 
A study on antimicrobial effect of sugars at low concentration
《Infectious Diseases Research》2025年第1期1-9,共9页Bhoj Raj Singh Mudit Chandra Monika Bhardwaj Varsha Jayakumar Akhilesh Kumar 
supported by grants received from CAAST-ACLH(NAHEP/CAAST/2018-19)of ICAR-World Bank-funded National Agricultural Higher Education Project(NAHEP).
Background:Although many sugars are known antibacterial in higher concentrations(>50%W/V)and a few at low concentrations too(≤1 mg/mL),most of the studies are limited to only a few reference isolates,therefore no con...
关键词：ENTEROBACTERIACEAE BACILLACEAE Enterococcaceae STREPTOCOCCACEAE Aeromonadaceae MANNOSE inositol MANNITOL 
The MYB61-STRONG2 module regulates culm diameter and lodging resistance in rice
《Journal of Integrative Plant Biology》2025年第2期243-257,共15页Yong Zhao Xianpeng Wang Jie Gao Muhammad Abdul Rehman Rashid Hui Wu Qianfeng Hu Xingming Sun Jinjie Li Hongliang Zhang Peng Xu Qian Qian Chao Chen Zichao Li Zhanying Zhang 
funded by the Biological Breeding-National Science and Technology Major Project(2023ZD0406803);the Agro ST Project(NK2022050103);the National Natural Science Foundation of China(32272123 and 32072036);the Hainan Provincial Natural Science Foundation of China(324QN358);the Chinese Universities Scientific Fund(2024TC189);the Postdoctoral Research Projects in Hainan Province(343812);the Hainan Seed Industry Laboratory and the China National Seed Group(B23YQ1517 and B23CQ15HP);the Special Plan for Key Laboratory of“Western Light Western cross team”(xbzg-zdsys202111);the 2115 Talent Development Program of China Agricultural University。
Lodging reduces grain yield and quality in cereal crops.Lodging resistance is affected by the strength of the culm,which is influenced by the culm diameter,culm wall thickness,and cell wall composition.To explore the ...
关键词：CELLULOSE CSLA5 lodging resistance MANNOSE MYB61 STRONG2 
Key amino acid residues govern the substrate selectivity of the transporter Xltr1p from Trichoderma reesei for glucose, mannose, and galactose
《Engineering Microbiology》2024年第4期1-11,共11页Wei Ma Shiyu Yuan Zixian Wang Kangle Niu Fengyi Li Lulu Liu Lijuan Han Xu Fang 
This work was supported by National Key R&D Program of China(No.2018YFA0901700);National Natural Science Foundation of China(No.32271526).
This research identified four amino acid residues(Leu174,Asn297,Tyr301,and Gln291)that contribute to sub-strate recognition by the high-affinity glucose transporter Xltr1p from Trichoderma reesei.Potential hotspots af...
关键词：Hexose transporter GLUCOSE GALACTOSE MANNOSE Transmembrane α-helix 7 Sugar transport Computer-aided screening 
Innate IgM antibodies to mannose in patients with gastric cancer
《Cancer Biology & Medicine》2024年第3期193-197,共5页Maxim Petrovich Nikulin Nadezhda Vladimirovna Shilova Alexander Dmitrievich Lipatnikov Ivan Sokratovich Stilidi Alexandra Vladimirovna Semyanikhina Nikolai Vladimirovich Bovin Nikolai Nikolaevich Tupitsyn 
supported by the Russian Science Foundation (Grant No. 22-24-00398)。
Gastric cancer(GC) remains one of the most common lethal diseases. Every year, about 1 million people fall ill and almost 800 thousand people die worldwide~1. Surgical treatment has reached its limit. The current adva...
关键词：GASTRIC cancer GASTRIC 
Size-dependent macrophage-targeting of mannose-modified rosiglitazone liposomes to alleviate inflammatory bowel disease被引量：2
《Chinese Chemical Letters》2024年第1期385-391,共7页Erjin Wang Run Han Mingyue Wu Yuan He Yaxin Cheng Jiahong Lu Ying Zheng 
the Macao Science and Technology Development Fund(No.0086/2021/A2);Shenzhen Fundamental Research Program(No.SGDX20210823103804030);the 2020 Guangdong Provincial Science and Technology Innovation Strategy Special Fund(Guangdong-Hong Kong-Macao Joint Lab,No.2020B1212030006);Guangdong Basic and Applied Basic Research Foundation(No.2022A1515012416).
Inflammatory bowel disease (IBD) is a refractory chronic intestinal inflammatory disease caused by a malfunction of immune system. As the key immune cells in the intestine, macrophages play an important role in mainta...
关键词：Macrophage targeting Liposome MANNOSE Particle size Inflammatory bowel disease 
Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P被引量：16
《Cell Research》2023年第12期904-922,共19页Yuan-li Ai Wei-jia Wang Fan-jian Liu Wei Fang Hang-zi Chen Liu-zheng Wu Xuehui Hong Yuekun Zhu Ci-xiong Zhang Long-yu Liu Wen-bin Hong Bo Zhou Qi-tao Chen Qiao Wu 
This work was supported by the National Natural Science Foundation of China and the Ministry of Science and Technology of China(U1905206,2020YFA0803403,82021003 to Q.W.,82073017 to W.J.W.,and 82122046,82072727 to X.H.).
Pyroptosis is a type of regulated cell death executed by gasdermin family members.However,how gasdermin-mediated pyroptosis is negatively regulated remains unclear.Here,we demonstrate that mannose,a hexose,inhibits GS...
关键词：CHEMOTHERAPY INTESTINE AMPK 
Application of mannose-modified fullerene immunomodulator selectively polarizes tumor-associated macrophages potentiating antitumor immunity
《Nano Research》2023年第11期12855-12863,共9页Haoyu Wang Lei Li Xinran Cao Mingming Zhen Chunru Wang Chunli Bai 
supported by the National Natural Science Foundation of China(No.92061123).M.M.Z.particularly thanks the Youth Innovation Promotion Association of CAS(No.2022036).
Polarization of tumor associated macrophages(TAMs)has been a promising therapeutic paradigm for tumor.However,how to achieve precise regulation of TAMs and high efficiency of tumor immunotherapy is still a huge challe...
关键词：FULLERENE MANNOSE macrophage targeting tumor-associated macrophage polarization cancer immunotherapy 
Mannose metabolism and immune regulation:Insights into its therapeutic potential in immunology-related diseases
《BIOCELL》2023年第11期2535-2546,共12页QINGPAN BU PING LI YUNFEI XIA XINPEI WEI KAI SONG 
supported by Natural Science Foundation Project of Jilin Provincial Department of Science and Technology(YDZJ202301ZYTS348)。
Mannose,a different isomer of the hydroxyl group at the C-2 position of glucose,shares the same transport carrier protein with glucose to enter cells and participate in the regulation of glucose metabolism.It affects ...
关键词：MANNOSE METABOLISM Immune cell Immune regulation 
Novel compound heterozygous variants in lectin mannose-binding 2-like gene identified in a Chinese autosomal recessive mental retardation-52(MRT52)patient with phenotype expansion
《Chinese Medical Journal》2023年第17期2107-2109,共3页Cong Zhou Xing Wei Yuanyuan Xiao Shanling Liu Jing Wang 
National Key Research and Development Program of China(No.2021YFC1005300);Program of Science and Technology Department of Sichuan Province(No.2022YFS0244)
To the Editor:Autosomal recessive mental retardation-52(MRT52,OMIM:616887)was first reported in 2016 and is characterized by global developmental delay,[1]severe intellectual disability(ID),speech disorder,and seizure...
关键词：EXPANSION EXACT delay 
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