神经内镜辅助显微镜切除鞍区肿瘤的临床研究  

Clinical study of neuroendoscope-assisted microscopes for the resection of Sellar region tumors

作　　者：周帅 李胜君[2] 苏文龙 王喆[2] 王寿先[2] Zhou Shuai;Li Shengjun;Su Wenlong;Wang Zhe;Wang Shouxian(Surgery Teaching,Weifang Medical College of Clinical Medicine,Shandong Weifang 261000,China;Department of Neurosurgery,Weifang People's Hospital,Shandong Weifang 261000,China)

机构地区：[1]潍坊医学院临床医学院外科教研室,山东潍坊261000 [2]山东省潍坊市人民医院脑科医院神经外科,261000

出　　处：《中国医师进修杂志》2019年第2期144-148,共5页Chinese Journal of Postgraduates of Medicine

基　　金：山东省医药卫生科技发展计划项目(2014WS0264).

摘　　要：目的探讨神经内镜辅助技术在鞍区肿瘤手术中的作用和价值。方法收集山东省潍坊市人民医院神经外科2015—2017年行神经内镜辅助显微镜切除鞍区肿瘤63例患者(神经内镜辅助组)的临床资料,及2013—2015年单纯经显微镜切除鞍区占位的76例患者(单纯显微镜组)的临床资料,通过对患者肿瘤切除率、术后并发症发生率及术后复发率进行比较,从而对手术效果进行评价。结果神经内镜辅助组及单纯显微镜组肿瘤的全切除率为95.24%(60/63)和80.26%(61/76),术后血管痉挛发生率为3.17%(2/63)和13.16%(10/76),神经损伤发生率为0(0/63)和6.58%(5/76),差异均有统计学意义(P<0.05)。两组术后感染、脑脊液漏发生率及术后复发率比较差异无统计学意义(P>0.05)。结论神经内镜辅助显微镜切除鞍区占位既能提高肿瘤全切率,又能降低并发症发生率。Objective To explore the role and value of neuroendoscopy-assisted microscope technique in the operation of sellar region tumor.Methods Sixty-three cases of saddle area treated by neuroendoscopy-assisted microscopy during 2015—2017 of neurosurgery in Weifang people′s hospital (neuroendoscopy-assisted microscope technique group) were collected and analyzed. Seven-six patients with sellar area treated by simple microscopic resection from 2013 to 2015(simple microscope group) were retrospectively analyzed. Tumor resection rate,postoperative complication rate and postoperative recurrence rate,the effect of operation was compared and evaluated.Results In the neuroendoscopy-assisted microscope technique group and simple microscope group,the total resection rate of tumor was 95.24%(60/63) and 80.26%(61/76),the incidence of vasospasm was 3.17 %(2/63) and 13.16%(10/76),and the incidence of nerve injury was 0(0/63) and 6.58%(5/76). There were significant differences (P<0.05). The postoperative infection,cerebrospinal fluid leakage and postoperative recurrence rate between two groups had no significant differences (P>0.05).Conclusions Endoscopic microscopically assisted resection of sellar area can not only increase the total resection rate of tumor,but also reduce the incidence of complications.

关 键 词：神经内镜 显微镜 鞍区占位 

分 类 号：R739.4[医药卫生—肿瘤]