尿激酶对中枢神经系统影响的研究进展  

The research progress of urokinase in central nervous system

作　　者：时敬国 朱战鹏[1] 曲丽梅[2] 刘立克[1] 王立天[1] 鲁质成[1] 王宏磊[1] 綦斌[1] Shi Jingguo;Zhu Zhanpeng;Qu Limei;Liu Like;Wang Litian;Lu Zhicheng;Wang Honglei;Qi Bin(Department of Neurovascular Surgery, the First Hospital of Jilin Universtiy, Changchun 130021, China;Department of Pathology, the First Hospital of Jilin Universtiy, Changchun 130021, China)

机构地区：[1]吉林大学第一医院神经血管病外科,长春130021 [2]吉林大学第一医院病理科,长春130021

出　　处：《中华实验外科杂志》2019年第2期381-383,共3页Chinese Journal of Experimental Surgery

基　　金：吉林省科技发展计划项目 (20160414039GH).

摘　　要：尿激酶是纤溶酶原的主要激活物之一,是近年来国内外研究的一个热点,根据尿激酶在病理和生理过程中发挥的作用,已将其应用于临床的众多领域,比如:肿瘤治疗、血管再通、组织修复等。其中,尿激酶在神经科领域得到广泛应用,包括溶栓和颅内血肿微创穿刺术作为血肿液化剂使用,本文就尿激酶在中枢神经系统方面的研究进展进行综述。Urokinase is one of the main activators of plasminogen. It has been a hot topic in recent years. According to the role of urokinase in pathological and physiological processes, it has been applied in many clinical fields, such as cancer treatment, vascular recanalization, tissue repair and so on. Urokinase has been widely used in neurology, including thrombolysis and minimally invasive puncture of intracranial hematoma as liquefying agent of hematoma. This article reviews the research progress of urokinase in central nervous system.

关 键 词：尿激酶 中枢神经系统 研究进展 

分 类 号：R741[医药卫生—神经病学与精神病学]