蜂房粗提物对致龋菌影响的实验研究  

The in vitro Study on Polistes Mandarinus' Effects on Cariogenic Bacteria

作　　者：黄正蔚[1] 肖悦[1] 刘天佳[1] 周学东[1] 李继遥[1] 詹玲[1] 

机构地区：[1]四川大学华西口腔医学院,四川成都610041

出　　处：《上海口腔医学》2002年第1期50-52,共3页Shanghai Journal of Stomatology

基　　金：UNILEVER公司英国研究中心资助

摘　　要：目的　研究蜂房粗提物对致龋菌生长、产酸及产胞外多糖的影响 ,探讨蜂房粗提物是否能有效调节口腔菌群的生态平衡。方法　测定蜂房粗提物对 3种口腔内变形链球菌、粘性放线菌和血链球菌的最低抑菌浓度 (MIC)。再测定低于MIC的 4个浓度的蜂房粗提物对上述 3种细菌产酸及产生水溶性和水不溶性多糖能力的影响。结果　蜂房粗提物对 3种细菌的生长、产酸均有一定的抑制作用 ,能够有效抑制变形链球菌和血链球菌产生水不溶性葡聚糖 ,但对粘性放线菌合成水不溶性葡聚糖无明显抑制作用。结论　蜂房粗提物能有效抑制变形链球菌、粘性放线菌和血链球菌的生长。Objective To study the role of Polistes mandarinus on the growth, acid generation and water insoluble glucan (WIG) production of Streptococcus mutans, Streptococcus sanguis and Actinomyces viscosus as a preparation for screening an effective agent to mediate the balance of oral microflora.Methods Streptococcus mutans 3a3,Streptococcus sanguis SB 179 and Actinomyces viscosus ATCC 19246 were chosen as the experimental bacteria. The effects of Polistes mandarinus on the growth, acid generation and glucan production were observed.Results Polistes mandarinus can inhibit the growth and acid generation of S.mutans, S.sanguis and A.viscosus, and the water insoluble glucan production of S. mutans and S.sanguis effectively.Conclusion Polistes mandarinus can inhibit the growth, acid generation and glucan production of oral bacteria effectively.

关 键 词：蜂房粗提物 变形链球菌 粘性放线菌 血链球菌 水不溶性葡聚糖 龋菌 

分 类 号：R780.2[医药卫生—口腔医学]