肝硬变患者血清微量元素测定的临床意义  

Clinical significance of detection of serum trace elements in patients with liver cirhosis

作　　者：姬艳[1] 秦建萍[1] 史兵伟[1] 

机构地区：[1]江苏省常州市中医医院检验科,213000

出　　处：《淮海医药》2002年第2期89-91,共3页Journal of Huaihai Medicine

基　　金：江苏省中医药局科研基金资助 (2 0 0 1- 19)

摘　　要：目的　探讨肝硬变患者血清中微量元素含量的变化。方法　应用原子吸收分光光度法测定了 10 2例肝硬变患者血清中硒 (Se2 + )、锌 (Zn2 + )、铜 (Cu2 + )、铁 (Fe2 + )、镁 (Mg2 + )含量 ,并与 6 2名正常健康人作对照。结果　肝硬变患者血清中 Se2 + 、Zn2 + 、Fe2 + 、Mg2 + 含量减少 (P<0 .0 1) ,而铜的水平则显著升高 (P<0 .0 1) ,Cu2 + / Zn2 +比值也显著升高 (P<0 .0 1)。结论　检测肝硬变患者血清中微量元素的变化有重要的临床意义。Objective To study the change of serum trace elements in patients with liver cirrhosis.Methods The levels of serum trace elements including selenium(Se 2+ ),zine(Zn 2+ ),copper(Cu 2+ ),ferric(Fe 2+ )and magnesium(Mg 2+ )were detected with atom absorption spectrophotometry in 102 cases of liver cirrhosis and 62 cases of healthy persons as control.Results Levels of Se 2+ ,Zn 2+ ,Fe 2+ and Mg 2+ in patients with liver cirrhosis were lower than those in normal control( P <0.01) while the levels of Cu 2+ ,Cu 2+ /Zn 2+ ratio were significantly higher( P <0.01).Conclusion Detection of trace elements levels change in patients with liver cirrhosis might be of important clinical significance.

关 键 词：肝硬化 微量元素 血清 原子吸收分光光度法 测定 

分 类 号：R575.2[医药卫生—消化系统] R446.1[医药卫生—内科学]