肝硬化伴院内感染自发性腹膜炎肾功能的变化与预后的关系  

The relationship between the changes of renal function and prognosis in cirrhotic patients with spontaneous bacterial peritonitis in hospital

作　　者：王义国[1] 阎明先[1] 张建娜[1] 

机构地区：[1]千佛山医院消化内科,山东济南250014

出　　处：《临床肝胆病杂志》2002年第2期91-92,共2页Journal of Clinical Hepatology

摘　　要：探讨肝硬化腹水患者院内感染自发性腹膜炎（ＳＢＰ）后肾功能的变化及其与预后的关系。观察１６２例院内感染ＳＢＰ患者肾功能的变化，分析肾功能损害（ＲＩ）的演变过程与死亡率的关系。结果显示有ＳＢＰ的患者肾功能损害（ＳＢＰ－ＲＩ）发生率明显高于无ＳＢＰ患者肾功能损害发生率（Ｐ＜０．０５），６３例发生ＳＢＰ－ＲＩ的患者中，进展型ＳＢＰ－ＲＩ占３６．５１％，稳定型ＳＢＰ－ＲＩ占３３．３３％，一过型ＳＢＰ－ＲＩ占３０．１６％，进展型和稳定型ＳＢＰ－ＲＩ死亡率（７３．９１％、４２．８６％）显著高于无ＳＢＰ－ＲＩ者（１６．１６％），一过型ＳＢＰ－ＲＩ（１５．７９％）不增加死亡率。引起ＳＢＰ－ＲＩ的主要原因是感染，它的高死亡率与肾损害程度直接相关。To study the changes of renal function in cirrhotic patients with spontaneous bacterial peritonitis (SBP) in hospi- tal and investigate the relationship between these changes and the patients prognosis, The changes of renal function and the relationship between renal impairment (RI) clinic course and mortality in 162 cirrhotic patients with SBP were ana- lyzed. The renal impairment incidence of cirrhotic patients with SBP (SBP - RI) is higher significantly than that of pa- tients without SBP (P < 0. 05). Among 63 patients occurred SBP - RI, 36. 51 % patients is progressive SBP - RI, steady SBP- RI 33 .33% and transient SBP - RI 30. 16%. The mortality of progressive and steady SBP - RI (73 .91%, 42. 86% ) are higher significantly while the mortality of transient SBP - RI (15. 79% ) is not higher than the mortality of patients without SBP - RI (16. 16% ). The mainly cause of SBP - RI is infection. The higher mortality of SBP - RI has correlation with renal impairment.

关 键 词：肝硬化 自发性腹膜炎 肾功能损害 预后 

分 类 号：R575.2[医药卫生—消化系统] R572.2[医药卫生—内科学]