肺癌发病的社会心理因素研究  

Psychosocial factors and lung cancer development

作　　者：张灿珍[1] 沈丽达[1] 王羽丰[1] 任宏轩[1] 李云霞[1] 赵玲[1] 和积高[1] 

机构地区：[1]昆明医学院第三附属医院肿瘤内科,650118

出　　处：《中国肺癌杂志》2002年第2期92-94,共3页Chinese Journal of Lung Cancer

基　　金：云南省自然科学基金资助 (97C0 58M)~~

摘　　要：目的　探讨与肺癌发病有关的社会心理因素 ,为进一步前瞻性研究打下基础。方法　选 118例经病理确诊 ,卡氏评分≥ 6 0分的肺癌患者为病例组 ,根据 1∶1配对原则 ,即与病例组相同性别、相同民族、相同职业、相同居住地点、年龄相差± 3岁、无身心疾患的健康人作为对照组。使用杨德森、张亚宁编制的“生活事件量表 (LES)”、肖水源编制的“社会支持评定量表”和Bond编制的“防御机制问卷 (DSQ)”分别对两组对象的生活事件、社会支持和防御机制进行问卷调查。结果　单因素分析中病例组吸烟、睡眠不足、饮酒、吃饭常伴烟酒、常吃腌制食品、生活无规律与对照组有统计学差异 (P <0 .0 5 ) ,生活事件评分、社会支持评分与对照组无统计学差异 ,但负性事件总分高于对照组 ,防御方式中不成熟因子与对照组有统计学差异 (P <0 .0 5 ) ;多因素分析中吸烟、睡眠不足进入癌症发病的 1∶1配对多元Logistic模型。结论　社会心理因素与肺癌发病有一定关系 ,防御方式中的不成熟因子为肺癌发病的社会心理因素 ,吸烟、睡眠不足、饮酒、吃饭常伴烟酒、常吃腌制食品、生活无规律为肺癌发病的危险因素。Objective To study the association between psychosocial factors and the development of lung cancer. Methods Case-control matched study was employed in the study. A standardized life event, social support and defense mechanisms interview was administered respectively. Total 118 lung cancer patients who were diagnosed pathologically were chosen as case group, and 118 matched healthy people were as control group. The pair had the same gender, the same race, and the same occupation, and lived in the same area, and the age difference between the two groups was ±3 years. Results Univariate analysis showed that smoking, defect of sleeping, alcohol consuming, smoking and drinking during meal, preserved food consuming, irregularity of life increased the risk of lung cancer development (P <0.05). The scores of life events, social support had no significant difference between two groups (P >0.05), but the scores of stress life events was higher in cancer group than that in control group. The immature factors of defense mechanisms in cancer group were higher than those in control group (P <0.05). Multiple qualified logistic regression showed that smoking and defect of sleeping were the main risk factors of lung cancer genesis. Conclusion There is certain association between psychosocial factors and lung cancer development. The immature defensive factor is the psychosocial factor of lung cancer genesis, and smoking, defect of sleeping, alcohol consuming, smoking and drinking during meal, preserved food consuming, irregularity of life are the risk factors of lung cancer.

关 键 词：肺癌 社会心理因素 生活事件 社会支持 防御机制 危险因素 

分 类 号：R734.2[医药卫生—肿瘤]