原发性胃肠道恶性淋巴瘤预后因素分析  

Analysis of Prognostic Factors on Primary Gastrointestinal Malignant Lymphomas

作　　者：郑玉萍[1] 侯淑玲[1] 刘阳[1] 杨斌[1] 

机构地区：[1]山西省肿瘤医院血液内科,太原市030013

出　　处：《中国肿瘤临床》2002年第4期258-261,共4页Chinese Journal of Clinical Oncology

摘　　要：目的:探讨影响原发性胃肠恶性淋巴瘤预后的因素。方法:对104例原发性胃肠恶性淋巴瘤的一般情况、病理类型、分期、治疗效果与5、10年生存率的相关性进行分析。结果:具有下列因素的患者:年龄大于60岁;瘤体直径大于10cm;瘤体突破浆膜或浸润周围脏器;病理分期Ⅲ、Ⅳ期;T细胞型;未接受手术治疗;初治未达CR,与其他患者对比并经统计学分析处理,结果显示:二者的5年生存率有显著性差异(P<0.05或P<0.01)。结论:除IPI指标外,肿块体积、病理分期与分型、临床分期、治疗手段以及初治效果,均是影响原发性胃肠恶性淋巴瘤预后的主要因素。Objective:To discuss the prognostic factors and influences on primary gas-trointestinal malignant lymphomas.Methods:The relationship between the general condition,pathological type,stage,therapeut ic effect of104cases of primary gastrointestinal malignant lym-phoma and the5-,10-year survival rates were analysed.Results:Poor prognosis could resulted in the following situations:The patients over60years old,with the tumor more than10cm in di-ameter,serosa or surrounding organs being infiltrated,pathological type of stageⅢorⅣ,with T type cells,had not been treated by operation and without reaching CR after initial treatment.After comparing with other patients and treated by statistical analysis,the results showed that there was significant difference between these two groups on5-year survival rates(P<0.05or P>0.01).Conclusion:Except the IPI index,the tumor size,pathological type,clinical stage,ther-apeutic modality and the initial curative effect all are the influencing factors to the prognosis of primary gastrointestinal malignant lymphoma patients.

关 键 词：原发性胃肠恶性淋巴瘤 病理因素 预后 

分 类 号：R735[医药卫生—肿瘤]