大肠癌术前血浆D-二聚体测定的临床价值  

The clinical value of determining D-Dimer in the plasma during preoperation of colorectal carcinoma

作　　者：李洋[1] 谭亚黔[1] 吴传新[1] 常正[1] 叶友坤[2] 赵红[2] 杜伟[2] 

机构地区：[1]重庆医科大学第二临床学院外科 [2]重庆医科大学第二临床学院外科实验室,重庆400010

出　　处：《重庆医科大学学报》2002年第1期56-58,共3页Journal of Chongqing Medical University

摘　　要：目的：探讨大肠癌术前血浆Ｄ－二聚体测定的临床价值。方法：８６例大肠癌患者术前测定血浆Ｄ－二聚体含量，从癌肿部位、临床分期、肿瘤组织学类型等方面进行探讨。结果：术前检测的阳性率为５８．１３％，结肠癌患者阳性率和均值明显高于直肠癌患者，且血浆Ｄ－二聚体水平亦与大肠癌临床分期、肿瘤组织学类型有一定关系。结论：大肠癌患者诊治过程中检测血浆Ｄ－二聚体，有利于了解患者纤溶状态，对诊断、临床分期及病情监测有一定参考价值。Objective: To explore the clinical value of determining plasma D-Dimer concentration in pre-operation patients with colorectal carcinoma. Methods: 86 patients with colorectal carcinoma were studied before operation. All patients' plasma D-Dimer was determined. The association of plasma D-Dimer concentration with position of carcinoma, clinical stages and pathologic type was studied. Results: The rate of positive results of plasma D-Dimer concentration before operation was 58.13%. The rate and the average value were significantly higher in patients with carcinoma of the colon than those in patients with carcinoma of the rectum. Significant linear correlation was found between D-Dimer concentration in plasma and clinical stages of colorectal carcinoma or pathologic type. Conclusion: It's useful to determine plasma D-Dimer concentration in patients with colorectal carcinoma and it's helpful to know patients' fibrinolysis state. Those results underscore the prognostic value of measurement of D-Dimer concentration in patients with carcinoma. It's referable to diagnosis, clinical stages and monitoring.

关 键 词：大肠癌 D-二聚体 测定 

分 类 号：R735.340.4[医药卫生—肿瘤] R730.43[医药卫生—临床医学]