Ki-67在非霍奇金淋巴瘤的表达及临床价值  

The expression of Ki-67 and its clinical value in non-hodgkin′s lymphoma

作　　者：薛宏伟[1] 潘祥麟[1] 董淑云[1] 

机构地区：[1]山东大学第二医院,山东济南250033

出　　处：《山东医药》2002年第6期14-15,共2页Shandong Medical Journal

摘　　要：采用免疫组化 SABC方法检测 Ki- 6 7在非霍奇金淋巴瘤 (NHL)石蜡包埋组织块中的表达水平。结果为 Ki- 6 7的表达与 NHL 组织学分类有关 (P<0 .0 5 ) ,与血清乳酸脱氢酶 (L DH)的水平相关 (P<0 .0 5 ) ,而与首发部位、年龄、临床分期、性别和有无全身症状无关 (P>0 .0 5 )。认为 Ki- 6 7对非霍奇金淋巴瘤临床分型。Ki 67 expressions were studied in 46 cases of paraffin embeded sections of non Hodgkin′s lymphoma(NHL)by an immurohistochemical assay(SABC) The Results show that Ki 67 expressions have significant relationship with the grades of hisology and the levels of lacti dehydrogenation enzym(P<0 05),non significant relationship with first suffering places,ages,clinical stages,genders and symptoms(P>0 05) We think Ki 67 expression has a great value in the dagnosis of NHL,grades of histology and clinical classifications

关 键 词：KI-67 非霍奇金淋巴瘤 免疫组织化学 

分 类 号：R733.1[医药卫生—肿瘤] R392.11[医药卫生—临床医学]