硝酸甘油经硬膜外导管鼻腔给药在小儿腭裂修补术的应用  

Application of nitroglycerin by nasal carity in cleft palaterepairing surgery

作　　者：刘双娣[1] 朱运莲[1] 潘建辉[1] 陈昆洲[1] 

机构地区：[1]安徽省立医院麻醉科,合肥230001

出　　处：《安徽医学》2002年第2期15-16,共2页Anhui Medical Journal

摘　　要：目的　减少小儿腭裂修补术中失血量。方法　 36例患儿在气管内麻醉下行腭裂修补术 ,随机分成两组 ,A组术中将硬膜外导管插入健侧鼻腔 0 .5～ 1.0cm ,间断推注硝酸甘油 (NTG 1ml=1.0mg)降压 ;B组为对照组 ,观察术中血压、心率及失血情况。结果　A组术中SBP、DBP明显低于B组 (P <0 .0 1) ,而血红蛋白高于B组 (P <0 .0 5 )。结论　NTG经鼻给药降压 ,方法简单、安全、效果确切。Objective To reduce blood loss in palate repairing surgery. Methods 36 patients with cleft palate were randomly divided into two groups.Group A received nitroglycerin(1 mg) intermitted by the normal nasal cavity with an epidural tube inserted into the cavity for controlled hypotension.Group B served as control group.The blood pressure,heart rate and blood loss volume were measured during operation.Results SBP and DBP in group A were lower singnificantly than those in group B(P<0.01),while haemoglobin in group A was higher than that in group B(P<0.05).Conclusion The controlled hypotension induced by the nasal administration of NTG could be an efficacious, simple and safe way to control blood loss in cleft palate repairing surgery.

关 键 词：手术 腭裂 硝酸甘油 失血 鼻腔给药 儿童 

分 类 号：R782.054[医药卫生—口腔医学]