脂肪肝合并胆结石患者血清胆碱酯酶水平的观察  

Changes of Serum CHE in Patients with Liver Lipidosis Combined with Cholelithiasis

作　　者：常艳敏[1] 范宏志[1] 王宗泽[1] 白铁环[1] 郑治纲[1] 

机构地区：[1]天津市南开医院检验科,300100

出　　处：《天津医药》2002年第4期223-224,共2页Tianjin Medical Journal

摘　　要：目的:观察脂肪肝合并胆结石患者血清胆碱酯酶(CHE)活力的变化。方法:酶动力法测定37例脂肪肝合并胆结石组及单纯脂肪肝组血清中的CHE,并与正常对照组进行比较。结果:脂肪肝组与脂肪肝合并胆结石组病人血清CHE水平高于正常对照组(P<0.01)。但单纯脂肪肝与脂肪肝合并胆结石组间无明显差异(P>0.05),脂肪肝合并由胆结石引起的严重胆道梗阻或胆管炎时,血清CHE水平低于正常及脂肪肝组(P<0.01)。结论:脂肪肝时病人血清中的CHE水平增加,但不能鉴别脂肪肝是否合并结石;如血清中CHE水平下降则提示有因结石而引起的胆道梗阻或炎症发生的可能。Objective: To observe the Changes of serum CHE in patients with liver lipidosis combined with cholelithiasis. Methods: Serum CHE was measured by kinetics method in 37 patients with liver lipidosis combined with cholelithiasis and 20 patients with liver lipidosis. The results were compared with that in normal control group. Results: The level of serum CHE was higher in patients with liver lipidosis and liver lipidosis combined with cholelithiasis than that in normal control group, and there was no significant difference between liver lipidosis and liver lipidosis combined with cholelithiasis groups. The level of serum CHE in cholelithiasis combined with obstruction or inflammation of bile duct was much lower than that in normal control or liver lipidosis groups. Conclusion: The level of serum CHE in liver lipidosis is higher than that in normal control group, but it can not be used to distinguish cholelithiasis. The bile duct obstruction or inflammation occurs if the serum CHE decreases.

关 键 词：脂肪肝 胆结石 胆碱酯酶 血清 酶动力法 测定 

分 类 号：R575.5[医药卫生—消化系统] R575.62[医药卫生—内科学]