猛性龋儿童变链菌分离株的初始粘附能力  

The initial adherence of Streptococci isolates from the children with rampant caries

作　　者：刘艳玲[1] 刘正[1] 冯希平 潘瑛[1] 马善奋[1] 

机构地区：[1]上海第二医科大学附属第九人民医院口腔预防科,200011

出　　处：《实用口腔医学杂志》2002年第2期102-104,共3页Journal of Practical Stomatology

基　　金：上海市卫生局百名跨世纪学科带头人培养计划基金资助 编号 :97BR0 1 4

摘　　要：目的 :探讨猛性龋儿童变链菌和远缘链球菌临床分离株的初始粘附能力。方法 :采用唾液包被羟磷灰石 (SHA)及同位素标记方法 ,检测猛性龋、非猛性龋、无龋儿童变链菌 (各 6株 )和远缘链球菌 (猛性龋儿童6株 ,非猛性龋和无龋儿童各 3株 )临床株对SHA的粘附情况。结果 :各组变链菌分离株之间及各组远缘链球菌分离株之间对SHA的粘附率无显著差异 ;在无蔗糖条件下 ,各组远缘链球菌分离株对SHA的粘附百分率均低于各组变链菌 ,差异有显著性 (P <0 .0 5 )。结论 :变链菌的初始粘附能力强于远缘链球菌 ;猛性龋儿童变链菌和远缘链球菌临床株对SHA的初始粘附能力与非猛性龋及无龋儿童无差别。?Objective:To determine the initial adhesive ability of Streptococcus mutans (S.mutans) and Streptococcus sobrinus (S.sobrinus) isolates taken from children with rampant caries.Methods:6 strains of S.mutans and 6 strains of S.sobrinus were isolated from randomly selected children with rampant caries;6 strains of S.mutains and 3 strains of S.sobrinus were isolated from children non rampant caries and from caries free children respectively.The initial adherence to saliva coated hydroxyapatite was analyzed by 3H labeled binding assay.Results:The initial adhesive ability to saliva coated hydroxyapatite among S.mutans strains and among S.sobrinus strains was similar ( P >0.05). S.sobrinus strains had significantly lower initial adhesive ability to saliva coated hydroxyapatite in the absence of sucrose than S.mutans (P <0.05).Conclusion: S.mutans has higher initial adhesive ability to saliva acquired pellicle in the absence of sucrose than S.sobrinus .The similar initial adhesive ability of S.mutans or S.sobrinus isolates to saliva coated hydroxyapatite in the absence of sucrose is not related the teeth with or without caries.

关 键 词：儿童 龋齿 变形链球菌 远缘链球菌 羟基磷灰石类 细菌粘附 

分 类 号：R788.1[医药卫生—口腔医学]