影响宫颈癌患者预后的临床病理因素分析  

Clinical and pathological factors influencing the prognosis of patients with cervical cancer

作　　者：袁利梅[1] 赵德英[1] 邱惠[1] 谢丛华[1] 张弓[1] 周福祥[1] 

机构地区：[1]武汉大学中南医院,肿瘤生物学行为湖北省重点实验室,武汉430071

出　　处：《山东医药》2014年第25期21-23,共3页Shandong Medical Journal

基　　金：湖北省杰出青年基金资助项目(2011CDA195)

摘　　要：目的通过分析宫颈癌患者的临床资料,探讨影响其预后的临床病理因素。方法回顾性分析195例宫颈癌患者的临床资料。结果单因素分析显示,宫颈癌临床Ⅰ期、Ⅱ期、Ⅲ期+Ⅳ期患者的5年生存率分别为88.2%、70.4%、39.3%,,不同分期间比较,P均<0.01;接受手术与未接受手术者的5年生存率分别为70.1%、40.5%,两者比较,P<0.01;腹膜后淋巴结转移与无腹膜后淋巴结转移者的2年生存率分别为20.4%、84.1%,两者比较,P<0.01。多因素分析显示,临床分期、手术、腹膜后淋巴结转移是影响宫颈癌患者总生存率的独立因素(P<0.05或<0.01)。结论临床分期、手术、腹膜后淋巴结转移与宫颈癌的预后显著相关。Objective To explore the key prognostic factors in patients with cervical cancer by analyzing the clinical data.Methods The clinical data of 195 patients with cervical cancer were retrospectively analyzed .Results According to the univariate analysis, the 5-year survival rates for stage Ⅰ,Ⅱ,Ⅲ＋Ⅳwere 88.2%, 70.4%and 39.3%, respec-tively （all P〈0.01）.The 5-year survival rate of patients undergoing surgery was higher than that of patients who did not undergo surgery （70.1%vs 40.5%, P〈0.01）.The 2-year survival rates of patients with and without retroperitoneal lymph node metastasis were 20.4%and 84.1%（P〈0.01）.Multivariate analysis demonstrated that stage , surgical treat-ment and retroperitoneal lymph node metastasis were independent prognostic factors for patients with cervical cancer .Con-clusion The clinical stages , surgical treatment and retroperitoneal lymph node metastasis are significantly associated with the prognosis of patients with cervical cancer .

关 键 词：宫颈肿瘤 生存率 预后 单因素分析 多因素分析 

分 类 号：R737.33[医药卫生—肿瘤]