聚甲基丙烯酸羟乙酯树脂对胆红素的吸附研究  

STUDIES ON THE ADSORPTION OF BILIRUBIN BY MACROPOROUS POLY(2-HYDROXYETHYL METHACRYLATE) ADSORBENTS

作　　者：卢玲[1] 袁直[1] 石可瑜[1] 何炳林[1] 

机构地区：[1]南开大学高分子化学研究所吸附分离功能高分子材料国家重点实验室,天津300071

出　　处：《离子交换与吸附》2002年第2期105-110,共6页Ion Exchange and Adsorption

基　　金：973计划资助项目课题编号: G1999064707

摘　　要：本文通过水相悬浮聚合制备了大孔交联聚甲基丙烯酸羟乙酯(PHEMA)树脂,研究了PHEMA树脂以及用乙醇胺功能基化后的PHEMA树脂对胆红素的吸附性能。结果表明,PHEMA树脂对胆红素的吸附性能受树脂孔结构、吸附温度、离子强度以及溶液中白蛋白的影响。该类吸附剂对胆红素有良好的吸附性能,其中用乙醇胺功能基化后的树脂表现出更好的吸附能力。Macroporous crosslinking poly(2-hydroxyethyl methacrylate) (PHEMA) resins were prepared by suspension polymerization. The adsorption properties of PHEMA for bilirubin were studied. The results showed that, the adsorption percentage was affected by pore distribution of resins, adsorption temperature, ion strength and the presence of albumin. PHEMA resins showed good adsorption properties for bilirubin, and PHEMA resin immobilizing ethanolamine had better adsorption capacity.

关 键 词：聚甲基丙烯酸羟乙酯树脂 吸附 胆红素 高胆红素血症 血液灌流 治疗 

分 类 号：R575.6[医药卫生—消化系统] R457[医药卫生—内科学]