大鼠心肌间质胶原的扫描电镜观察  

OBSERVATION ON THE COLLAGEN OF MYOCARDIAL INTERSTITIUM IN RATS BY SCANNING ELECTRON MICROSCOPE

作　　者：陈小迅[1] 张书永[1] 田珑[1] 陈莉[1] 夏家骝[1] 

机构地区：[1]北京大学基础医学院解剖学与组织学胚胎学系,北京100083

出　　处：《解剖学报》2002年第2期195-198,共4页Acta Anatomica Sinica

基　　金：北京医科大学基础医学院凯华基金资助项目 (97 0 10 )

摘　　要：目的　探讨大鼠心肌间质胶原网络的形态构筑及其功能意义。　方法　利用四氧化锇和氢氧化钠细胞浸渍方法 ,于扫描电镜下对大鼠心肌间质胶原进行观察。　结果　粗细不等的胶原纤维相互交织充填于心肌细胞及毛细血管间。粗胶原纤维平行或斜跨于细胞和血管表面 ,形成粗大的框架式结构 ;细胶原纤维卷曲蓬松 ,呈鞘状包裹心肌细胞和毛细血管 ,相邻的胶原鞘彼此融合形成间隔。　结论　心肌间质胶原网络由粗大的框架式结构和纤细的胶原网组合而成 。Objective To study the morphological construct of the myocardial collagen network and its functional relationship in rats. Methods The collagen of myocardial interstitium was observed by scanning electron microscope after myocardium was treated by cell maceration using OsO 4 and NaOH. Results The collagen fibers with different diameters interlaced and filled between cardiac myocytes and capillaries. The thick collagen fibers ran parallel and aslant the surface of the myocardial cells and vessels, then formed the thick frameworks. The winding and curved thin collagen fibers wrapped up the cardiac myocytes and capillaries as sheath. The adjacent collagen sheaths united together and formed the compartment.Conclusion The collagen network of myocardial interstitium is composed of thick framework and thin collagen net. The collagen network might play important roles in preserving the normal function of heart. [

关 键 词：心肌细胞 胶原网络 扫描电镜 心肌间质胶原 动物实验 心脏 

分 类 号：R322.11[医药卫生—人体解剖和组织胚胎学]