血清β-葡萄糖醛酸酶测定在早期肝癌诊断的意义  

DIAGNOSIS SIGNIFICANCE OF SERUM β-GLUCURONIDASE DETECTION IN PATIENTS WITH EARLY HEPATIC CARCINOMA

作　　者：张弘[1] 郑锐 杨波 朱善德 于安民 

机构地区：[1]中国医科大学基础医学院病理解剖学教研室 [2]第一临床学院呼吸内科,沈阳110001 [3]沈阳军区总医院肝胆外科,沈阳110015

出　　处：《中国组织化学与细胞化学杂志》2000年第4期422-424,共3页Chinese Journal of Histochemistry and Cytochemistry

基　　金：辽宁省科技攻关计划社会发展基金资助项目!(No.982 2 5 0 0 3)

摘　　要：研究血清 β-葡萄糖醛酸酶 (β- G)活性测定对早期肝癌的临床意义。用 EL ISA技术 ,测定早期肝癌患者血清 β- G活性 ,并对早期肝癌患者治疗前、后血清 β- G活性变化进行检测。结果表明早期肝癌患者血清 β- G活性明显高于对照组 ,(P<0 .0 1)。早期肝癌患者经手术切除或介入治疗后 ,血清 β- G活性明显降低 ,(P<0 .0 5 )。结果显示血清 β- G检测对早期肝癌的诊断、治疗的判断均有一定的意义。To study the clinical significance of serum β glucuronidase (β G) detected in patients with early hepatic carcinoma, the ELISA method was used to detect the activity of serum β G and the regularity of the change of serum β G in patients with early hepatic carcinoma before and after treatment Results showed that serum activity of β G was significantly higher in the group of early hepatic carcinoma than that of normal control ( P <0 01) The serum activtiy of β G was markedly decreased after operation or interventional therapy ( P <0 05) The findings showed that detection of serum β G is significant in diagnosis and in judgement of treatment efficiency of early hepatic carcinoma \;

关 键 词：诊断 血清 Β-葡萄糖醛酸酶 ELISA 治疗 早期肝癌 

分 类 号：R735.7[医药卫生—肿瘤]