三甲护肝汤治疗晚期肝癌的临床研究  被引量:1

Clinical Study on Effect of Sanjia Hugan Decoction in Treating Advanced Liver Carcinoma

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作  者:张国熙[1] 

机构地区:[1]东莞市莞城医院,广东东莞523000

出  处:《辽宁中医杂志》2002年第5期267-268,共2页Liaoning Journal of Traditional Chinese Medicine

摘  要:观察三甲护肝汤对晚期肝癌的临床疗效 ,随机分为二组 ,治疗组 5 0例 ,用三甲护肝汤加支持疗法 ,对照组40例 ,只予支持疗法 ,观察两组的生存质量、生存时间、肿瘤体积变化的差异。结果 ,治疗组的生存质量评价 :自理 2 7例 (5 4% ) ,半自理 8例 (16 % ) ,不能自理 15例 (30 % ) ;对照组 ,自理 11例 (2 7% ) ,半自理 9例 (2 2 % ) ,不能自理 2 1例(5 2 % ) ,两组对比P <0 0 5。生存时间对比 ,治疗组最长 2 5个月 ,平均 (11 9± 6 5 )月 ;对照组最长 15个月 ,平均 (6 8±4 3)月 ,两组对比P <0 0 1。肿瘤稳定时间变化 ,治疗组平均稳定期 (8 9± 6 5 )月 ;对照组平均稳定期 (1 8± 4 3)月 ,两组对比P <0 0 1,表明由养阴扶正 。Objective:To observe the clinical effects of Sanjia Hugan Decoction(SJHGD)in treating advanced liver carcinoma.Methods:Ninety patients were randomly divided into the treated group(50 patients)treated by Supporting Treatment added SJHGD,and the control group (40 patients) treated by Supporting Treatment alone.The quality of life,live time and changes of tumor′s volume in the two groups were observed and compared.Results:After treatment the quality of life in the treated group was 54% self-helped,16% half-self-helped and 30% not self-helped,while that in the control group was 27%,22% and 52% respectively.The quality of life in the former was superior to that in the latter(P<0.05).The longest living time in the treated group was 25 months,mean (11.9±6.5) months and in the control group,15 months,mean (6.8±4.3) months.Living time in the former was obviously longer than that in the latter(P<0.01).Comparing the changes of tumor′s stable time,the mean of the treated group was (8.9±6.5) and that of the control group was (1.8±4.3).The difference between the two groups was significant(P<0.01).Conclusion:Made of medicine moisturizing yin and clearing away the heat and toxic materials,SJHGD was effective in certain degree in improving the quality of life of the patients with advanced liver carcinoma.

关 键 词:晚期肝癌 三甲护肝汤 生存质量 

分 类 号:R735.7[医药卫生—肿瘤]

 

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