复方丹参注射液防止平阳霉素化疗后所致肺间质纤维化的临床研究  

A clinical study of Salvia Miltriorrhiza (SM) on preventing the pulmonary fibrosis induced by pinyangmycin

作　　者：张茹慧[1] 徐洋[1] 刘文书[1] 刘敬华[1] 

机构地区：[1]吉林大学口腔医院,长春130041

出　　处：《现代口腔医学杂志》2002年第3期254-255,共2页Journal of Modern Stomatology

摘　　要：目的　应用复方丹参注射液 (SM)可防止平阳霉素 (BLM)化疗后肺纤维化的发生。方法　对 6 7例头颈部鳞癌患者进行术前术后平阳霉素化疗的同时 ,使用复方丹参注射液可防止肺部并发症出现。结果　其中 5 4例并一年随访 ,拍片检查 ,无肺纤维化症状、体征 ,拍片可见两肺野清晰 ,肺纹理走行规整。Objective To investigate the effect of Salvia Miltriorrhiza on prevention of the pulmonary fibrosis induced by pinyangmycin.Methods 67 cases of patients with squamous cell carcinoma received Salvia Miltrorrhiza and chemotherapy before and after operation.Chest X-ray was conducted at one year follow up.Results 54 cases were followed up for one year and no pulmonary fibrosis occured.Conclusion Salvia Miltriorrhiza may be useful in prevention of pulmonary fibrosis.

关 键 词：复方丹参注射液 防止 平阳霉素化疗 临床研究 肺纤维化 治疗 头颈部鳞癌 

分 类 号：R739.91[医药卫生—肿瘤] R563.13[医药卫生—临床医学]