重性抑郁症与心境恶劣障碍的神经心理学对比研究  

A comparison between major depression and dysthymia on neuropsychological tests.

作　　者：周茹英[1] 刘协和[1] 

机构地区：[1]四川大学华西医院心理卫生中心,610041

出　　处：《四川精神卫生》2002年第1期4-7,共4页Sichuan Mental Health

摘　　要：从神经心理学角度探讨重性抑郁症和心境恶劣障碍之间认知症状的异同。方法　对符合DSM-Ⅳ的 40例重性抑郁症、36例心境恶劣障碍和 37例正常对照使用WAIS智力全套测验、WMS逻辑记忆与视觉再生测验、STROOP、词汇流畅性、延线测验A、B、汉诺塔、威斯康辛卡片分类测验改良版 (M -WCST)进行评测。结果　两种抑郁障碍均存在认知功能损害 ,重性抑郁症患者的认知损害有较重且范围较宽的认知损害 ,涉及双侧额叶、双侧颞叶、边缘系统及右侧顶叶。心境恶劣患者的损害多局限于额叶皮质。重性抑郁症“伴忧郁特征”的患者较“不伴忧郁特征”的患者存在更多涉及右侧半球的认知损害。结论　精神病性抑郁症较非精神病性抑郁症有普遍更严重的认知损害。Objective To compare the cognitive functions between major depression and dysthymia.Method 40 patients with major depression,36 with dysthymia according to DSM-Ⅳ,and 37 normal controls were tested by WAIS,Logical Memory and Visual Reproduction subsets of WMS,Stroop Test,Verbal Fluency,Trails Making,Tower of Hanoi,and Modified version of Wisconsin Card Sorting Test.Results Both of the depressed patients have cognitive dysfunctions in the neuropsychological tests.Patients with major depression have severer and wider impairments than those of dysthymic patients.Conclusion The 'melancholic' and 'psychotic' features bring to the patients more impairment in neuropsychologic tests.

关 键 词：重性抑郁症 心境恶劣 认知功能 神经心理学测验 

分 类 号：R749.4[医药卫生—神经病学与精神病学]