中国儿童亚临床维生素A缺乏患病率及其影响因素  

Prevalence of subclinical vitamin A deficiency and its affecting factors in 8 669 children of China

作　　者：谈藏文[1] 马官福[1] 林良明[1] 刘春燕[1] 刘玉琳[1] 蒋竞雄[1] 任桂珍[1] 王娅琳[1] 郝轶梅[1] 何璐[1] 姚京萍[1] 

机构地区：[1]首都儿科研究所儿童营养研究室,北京100020

出　　处：《中华预防医学杂志》2002年第3期161-163,共3页Chinese Journal of Preventive Medicine

基　　金：联合国儿童基金会资助 (CRQ 0 0 0 0 3 3 3 9 0 )

摘　　要：目的　探讨儿童亚临床维生素A缺乏 (SVAD)的现状及其影响因素。方法　抽取全国14个省、市、自治区的 86 6 9名 6岁以下儿童。询问其膳食、健康、家庭情况。以微量荧光法测定其血清维生素A(VA)含量。结果　儿童血清VA均值为 (1 0 6± 0 33) μmol/L ,SVAD患病率为 11 7% ,可疑SVAD患病率为 39 2 %。其SVAD及可疑SVAD患病率随所在地区国内生产总值和家庭年人均收入的增高、母亲受教育程度的增高、儿童年龄的增长而降低。儿童SVAD及可疑SVAD患病率 ;农村(15 0 % )高于城市 (5 2 % ) ,母亲是少数民族者 (2 2 6 % )高于母亲是汉族者 (8 7% ) ,采血前 1周内未摄入富含VA食物者 (12 6 %～ 2 2 6 % )均高于每日摄入者 (4 1%～ 10 0 % ) ,采血前 2周内曾患呼吸道感染、发热、腹泻者 (15 2 %～ 2 0 3% )非常显著高于未曾患病者 (10 1%～ 11 1% )。logistic回归分析显示 ,儿童所在地区及家庭的经济状况不好、家居农村、母亲是少数民族、小年龄、未食乳类、采血前 2周内曾患呼吸道感染、发热是其SVAD的危险因素。结论　 5 0 9%的儿童存在或可能存在VA营养问题。儿童SVAD是多种因素在不同程度上起作用的结果。Objective The survey will reveal current status of subclinical vitamin A deficiency (SVAD) and explore its affecting factors in children of China Methods Totally 8 669 children aged under 6 years were randomly selected from 14 provinces for clinical examination, health and dietary questionnaire and serum level of vitamin A measurement with fluorescence method The cut off value for SVAD was defined as ≤0 70 μmol/L. Results Prevalence of SVAD was 11 7% and that of suspected SVAD 39 2% in all subjects, which decreased with the increase of gross domestic product, average annual family income, mother′s schooling and children′s age Prevalence of SVAD and suspected SVAD higher in rural areas(15 0%)than in urban areas(5 2%),and higher in children with a minority mother (22 6%) than in those with a Han nationality mother(8 7%) Prevalence of SVAD and suspected SVAD was higher in children whose blood samples were collected within one week in taking vitamin A rich food(12 6%-22 6%)than those in taking vitamin A daily(4 1%-10 0%), and higher in children suffering from respiratory infection, fever and diarrhea two weeks before their blood collection(15 2%-20 3%) than in those without those diseases(10 1%-11 1%) Logistic regression analysis showed that poor family economic status, living in rural areas, children with a minority mother, younger age, no dairy milk products intake, and respiratory infection and fever all were risk factors for SVAD Conclusions More than half of children under six years old in China (50 9%) had vitamin A nutrition problem Varied factors played roles to different extent in SVAD in children

关 键 词：维生素A缺乏 危险因素 儿童 膳食调查 患病率 

分 类 号：R181.32[医药卫生—流行病学]