脑静脉系统血栓消溶时间与临床关系的动态研究  

Relationship between thrombolysis time of cerebrovenous system and clinicals

作　　者：元小冬[1] 米振洲[1] 李舒[1] 赵新田 袁建新[1] 郭忠芹[1] 赵丽君[1] 马兴常 林自更 

机构地区：[1]华北煤炭医学院附属开滦医院神经内科,河北唐山063000 [2]唐山新区医院

出　　处：《华北煤炭医学院学报》2002年第3期273-275,共3页Journal of North China Coal Medical College

基　　金：1998年唐山市科学明星计划项目 (编号 982 0 74)

摘　　要：1目的　研究脑静脉系统血栓消溶再通的时间和方向性及其与临床改变和溶栓等治疗方法间的关系。2方法　对 11例脑静脉系统血栓形成患者进行 2～ 6年动态追踪研究 ,分析其不同阶段的临床特征 ,并进行脑 CT和脑 MR扫描 ,以观察脑静脉系统血栓的状态。 3结果　本病早期多以头痛、呕吐等高颅压症状起病 ,然后逐渐出现局灶性神经系统定位体征 ;动态研究表明 ,脑静脉窦血栓在早期逐渐加长 ,在发病 2 0 d已开始消溶 ,且由血栓近心端开始 ,较小血栓发病 30 d即可完全再通 ,较大血栓 6 0 d内也可完全消溶再通 ,而溶栓治疗则可明显加速其消溶过程。 4结论　脑静脉系统血栓由血栓近心端开始 ,在发病 2 0 d已开始消溶 ,6 0 d内可完全消溶再通 ,临床应尽早进行溶栓和预防并发症的治疗 。Objective To study the relationship between the time and direction of thromb dissolved,blood recirculated of cerebrovenous system and clinical changes,and the time and way of thrombolysis treatment.Methods 11 cases with thrombosis of cerebrovenous system were observed followed-up two to six years.Clinical demonstration was analysed and CT and MR scanning of brain were conducted.Results The disease occured with the high intracranial pressure symptome-headache and vomitting in early period,then gradually appeared fix sighs of nervous system in local site.It showed that thromb in cerebrovenons sinus gradually got longer in early period.It started to dissolve after 20 days,and began to dissolve from the terminal towards heart.The cases with smaller thromb recovered after 30 days,the larger ones 60 days.Thrombolysis treatment could obviously accelerate the procession of dissolving.Conclusions Thromb of cerebrovenous system started to dissolve from the terminal towards heart after 20 days and completely dissolved after 60 days.Thrombolysis treatment and prevention of acompany symptome should be conducted in early period.

关 键 词：脑静脉系统 血栓形成 脑MR扫描 血栓消溶 

分 类 号：R743.32[医药卫生—神经病学与精神病学]