酪立宁胶囊治疗急慢性腹泻70例  

The efficacy of Laolining capsule in treatment of 70 patients of acute and chronic diarrhea

作　　者：程留芳[1] 甘立平[2] 董蕾[3] 汤旦林[4] 崔云龙 梅巍[2] 万阜昌 

机构地区：[1]解放军总医院,北京100853 [2]北京军区总医院,北京100070 [3]西安医科大学第二附属医院,西安710004 [4]中日友好医院,北京100029

出　　处：《中国新药杂志》2002年第4期317-319,共3页Chinese Journal of New Drugs

摘　　要：目的 :观察酪立宁胶囊对急慢性腹泻的临床疗效和安全性。方法 :采用多中心随机双盲双模拟对照试验。酪立宁胶囊 70例 ,po 1.2 6 g ,bid ;对照药米雅片 70例 ,po 1.0 5 g ,bid。疗程急性腹泻 3～ 7d ,慢性腹泻 14～2 1d。结果 :酪立宁胶囊治疗急性腹泻有效率为 98.0 % (40 / 4 1) ,慢性腹泻有效率为 10 0 % (2 9/ 2 9) ;对照药米雅片分别为 98.0 % (40 / 4 1)和 86 .0 % (2 5 / 2 9)。二药疗效均无显著性差异 (P >0 .0 5 ) ,也均未出现不良反应。结论 :酪立宁胶囊是安全有效的治疗急性、慢性腹泻的微生态制剂 。Objective:To observe the safety and efficacy of Laolining (LLN) capsule in treatment of acute and chronic diarrhea.Methods:A multi center,randomized,double blind,double dummy and controlled trials were adopted in the studies.140 patients were divided to receive twice daily LLN capsule of 1.26g,or twice daily Miya tablet of 1.05g for 3～7d or 14～21d.Results:For treatment of acute and chronic diarrhea,the effective rate of LLN capsule was 98.0%(40/41)and 100%(29/29),and Miya tablet was 98.0%(40/41),86.0%(25/29),respectively in studies.No significant differences were observed between LLN capsule and the control drug (Miya tablet) in studies.Conclusion:LLN capsule is an effective agent in treatment of acute and chronic diarrhea, the safety and efficacy of LLN capsule are similar to that of Miya tablet.

关 键 词：酪立宁 急慢性腹泻 安全性 

分 类 号：R975[医药卫生—药品]