多梗死性痴呆危险因素的病例对照研究  

Case-control Study on Risk Factors of Multiple-infarct Dementia

作　　者：刘汝宏[1] 

机构地区：[1]胜利油田中心医院神经内科,山东东营257034

出　　处：《中国慢性病预防与控制》2002年第2期55-56,60,共3页Chinese Journal of Prevention and Control of Chronic Diseases

摘　　要：目的探讨各危险因素与多梗死性痴呆 (mutiple- infarctdementia,MID)的关系。方法 1∶ 1病例对照研究方法对 1 0 2例 MID患者及对照作调查研究 ,应用条件 Logistic回归分析技术推断其发病危险因素。结果 MID与下列 5种因素关系密切 :高血压病 (OR=3.56) ,心脏病 (OR=3.0 1 ) ,眼底动脉硬化 (OR=2 .73) ,受教育程度 (OR=2 .67) ,脂蛋白(a) (lipid protein- a,LP(a) ) (OR=2 .58)。结论高血压病、心脏病、眼底动脉硬化、受教育程度、LP(a)可能是 MID的主要危险因素。不同地区 MID流行因素不同 。Objective To explore the risk factors for multiple infarct dementia(MID).Methods A 1∶1 matched case control study on 102 cases of multiple infarct dementia and 102 matched controls was conducted,and multivariate analysis with fitting conditional Logistic model was used to infer the influence factors. Results It was shown that MID was closely related to five factors:hypertension( OR =3 56),heart disease ( OR =3 01),fundus arteriosclerosis ( OR =2 73),the training grade ( OR =2 67),and lipid protein a(LP(a))( OR =2 58). Conclusion Hypertension,heart disease,fundus arteriosclerosis,the low training grade and high LP(a) were main risk factors for MID.Epidemical factors of MID were various in different areas,the preventive measures should be pertinent.\;

关 键 词：多梗死性痴呆 危险因素 病例对照研究 

分 类 号：R749.160.2[医药卫生—神经病学与精神病学]