淋巴瘤患者外周血大颗粒淋巴细胞及淋巴细胞微核的分析  

A study on large granular lymphocyte and lymphocyte micronuclei in peripheral blood of lymphomas patients

作　　者：黄平[1] 李季蓉[1] 才秀莲[1] 

机构地区：[1]遵义医学院组织胚胎学教研室,贵州遵义563003

出　　处：《遵义医学院学报》2002年第1期14-15,共2页Journal of Zunyi Medical University

摘　　要：目的　探讨淋巴瘤患者外周血大颗粒淋巴细胞 (LGL)及淋巴细胞微核的变化及意义。方法　对 15例淋巴瘤患者及 2 0例输血人员外周血做血涂片 ,瑞氏染色 ,光学显微镜观察。结果　淋巴瘤患者外周血中LGL百分率为 2 4.0 1%± 7.5 1% ,对照组LGL百分率为 5 .6 5 %± 2 .6 0 % ,差异有显著性 (P <0 .0 0 1)。淋巴瘤患者外周血中淋巴细胞微核率为 0 .87‰ ,对照组为 0 .6 5‰ ,差异无显著性 (P >0 .0 5 )。结论　淋巴瘤患者外周血中LGL的变化对病人机体的免疫状态及预后等有一定的临床意义。Objective To study the variety and signifecance about large granular lymphocyte(LGL) and lymphocyte micronuclei in peripheral blood of lymphomas patients. Methods Peripheral blood smears of 15 cases lymphpmas patients and 20 cases blood donor ,were stained by Wrights method and examined by light microscopy. Results The peripheral blood of lymphomas patients large granular lymphocyte percentage is 24.01%±7.51%, matched control LGL percentage is 5.65%±2.60%, the difference have to show(P<0.001). The peripheral blood of lymphomas patients lymphocyte micronuclei rate is 0.87‰, matdhed control is 0.65‰(P>0.05). Conclusions The lymphoma get the clinical significance that machines immunity appearance and prognosis.

关 键 词：淋巴瘤 外周血 大颗粒淋巴细胞 微核 

分 类 号：R733.4[医药卫生—肿瘤]