局限性Castleman病特征性钙化的CT表现和病理学对照  

Characteristic calcification of localized Castleman′s disease:CT and histopathologic appearance

作　　者：王仁贵[1] 那佳[2] 宾怀有[3] 朱学俊[4] 王仪生[1] 唐光健[1] 蒋学祥[1] 高玉洁[1] 

机构地区：[1]北京大学第一医院医学影像科,100034 [2]北京大学第一医院病理科,100034 [3]广西柳州市工人医院放射科 [4]北京大学第一医院皮肤科,100034

出　　处：《中华放射学杂志》2002年第4期354-356,共3页Chinese Journal of Radiology

摘　　要：目的　讨论局限性Castleman病特征性钙化的CT表现和病理学特征。方法　 2 2例局限性Castleman病中有 5例合并钙化。瘤灶位于后腹膜腔者 3例 ,前纵隔者 2例。均经CT扫描和手术病理证实。结果　 2 2例局限性Castleman病 5例有钙化 ,CT均表现为中央性分布的分支状或斑点状 ,其中 1例伴有周边壳状钙化。增强扫描均呈显著均匀强化。病理学分型为透明血管型 4例 ,中间型1例 ,分支钙化均沿增生的小血管分布。结论　中央性分支状钙化和病灶显著均匀强化是局限性Castleman病定性诊断的重要特征。Objective To correlate the CT findings and pathologic appearance of characteristic calcification of localized Castleman′s disease. Methods Calcification was detected on CT in 5 of 22 patients with localized Castleman′s disease. The patients were 2 men and 3 women, ranging in age from 21 to 46 years. Castleman′s tumor manifested as a solitary and huge mass in the retroperitoneum ( n =3) and mediastinum ( n =2). The diagnoses were confirmed by surgery in all patients. Results On CT scan, the calcification has an arborizing and(or) flocculent pattern and central location in 5 patients and circumferential distribution in 1 patient. All the tumors showed marked enhancement after contrast administration at arterial phase and delay scan. Histologically, the lesions were demonstrated as the hyaline vascular type ( n =4) and mixed type ( n =1). All the central arborizing calcification was distributed in hyalinized and sclerosed small vessels. Conclusion Central arborizing calcification and marked enhancement after contrast administration are most important and specific findings in definite diagnosis of localized Castleman′s diseases.

关 键 词：局限性CASTLEMAN病 特征性钙化 CT表现 病理学 巨淋巴结增生 钙质沉着症 

分 类 号：R730.44[医药卫生—肿瘤]