男性鼻咽癌患者血液流变性异常的临床观察(附64例报告)  

Clinical Observations on Hemorheological Property in 64 Cases of the Male Patients with Nasopharyngeal Carcinoma

作　　者：曹伟建[1] 马军[2] 常则灵[2] 钱义兵[1] 

机构地区：[1]安徽省立医院,安徽省立体定向神经外科研究所神经生化室,安徽合肥230001 [2]安徽省立医院放疗科,安徽合肥230001

出　　处：《河南肿瘤学杂志》2002年第3期164-166,共3页Henan Journal of Oncology

摘　　要：目的　探讨血液流变学在鼻咽癌中的变化规律 ,评价其临床意义。方法　测定各期男性鼻咽癌患者血液流变学 8项指标。结果　各期鼻咽癌患者全血低切 (10S-1)粘度、血浆 (12 0S-1)粘度、纤维蛋白原、血沉和血沉方程K值均高于正常对照组 (P <0 0 1和P <0 0 5 ) ;Ⅰ～Ⅱ期以 3项指标异常者为主 ,Ⅲ期和Ⅳ期以 4项指标异常者为主。结论　血液高粘、高凝状态是鼻咽癌重要的病理机制之一 。Objective To investigate the rule and clinical significance of the changes of hemorheology in patients with nasopharyngeal carcinoma. Methods 8 hemorheological parameters in male patients were examined. Results The levels of whole blood low-shear viscosity, plasma viscosity,erythrocyte sedimentation and equation K value of erythrocyte sedimentation of the patients in different stages were all obviously higher than those of normal control group ( P <0 01 and P <0 05). Most of Ⅰ～Ⅱ stage patients account for 3 of 8 abnormal parameters examined while most of Ⅲ and Ⅳstage patients account for 4 abnormal parameters.Conclusions The state of hyperviscosity and hypercoagulability of blood is one of the important mechanisms of pathology in nasopharyngeal carcinoma and does not become heavier with the increase in stage.

关 键 词：男性 临床观察 鼻咽癌 血液流变学 

分 类 号：R739.63[医药卫生—肿瘤]