食管拉网细胞学诊断172例近癌的随诊  

The Follow up of 172 Cases of Near Cancer Diagnosed by Esophageal Exfoliative Cytology

作　　者：陈志峰[1] 丁镇伟[2] 张俊会 李绍森 王继信[2] 

机构地区：[1]河北省肿瘤研究所,河北石家庄050051 [2]中国医科院肿瘤研究所,北京100021 [3]磁县中医院,河北磁县056500 [4]磁县肿瘤防治所,河北磁县056500

出　　处：《河南肿瘤学杂志》2002年第3期169-170,共2页Henan Journal of Oncology

摘　　要：目的　探讨食管癌前病变近癌的癌变危险度和细胞学整体疗效。方法　以细胞学诊断的 172例近癌为观察对象 ,随机分为治疗组和对照组 ,治疗组口服中药增生平 ,对照组服用安慰剂 ,服药 3 8个月做细胞学复查。疗效统计采用Ridit分析和RR。结果　RR =0 76,95 %CI=(0 2 4～ 2 44 )。Ridit=0 5 ,95 %CI =(0 3 7～ 0 62 )。结论　细胞学诊断的近癌RR高 。Objective To explore relative risk(RR) and cytology of general grade effects for near cancer of precancerous lessions of the esophagus. Method 172 cases with near cancer were sampled and examined by esophageal exfoliative cytology.These cases are randomly divided into treatment group and control group. In the treatment group,the chinese herbal medicine Zengshengping was given to patients with near cancer, placebol was given to the control group. After administration of drug for 38 months, the esophageal cytological reexamination was repeated,using the RR and Ridit analysis for the effectiveness. Results RR=0.76,95%CI=(0.23～2 44);Ridit=0.50,95%CI=(0.37～0.62).Conclusion It indicated that RR was higher in the patient with nearcancer and not enough ideal for pure drug inhibitory therapy.

关 键 词：食管拉网细胞学 诊断 食管癌 近癌 生物学特性 

分 类 号：R735.1[医药卫生—肿瘤]