老年恶性血液病患者医院感染78例临床分析  

Clinical analysis on nosocomial infection of 78 elderly patients with hematological malignant diseases

作　　者：齐咏[1] 李志英[2] 贺立山[2] 赵媛英[2] 

机构地区：[1]西安交通大学第一医院,陕西西安710061 [2]新乡医学院第一医院,河南新乡453003

出　　处：《新乡医学院学报》2002年第2期97-99,共3页Journal of Xinxiang Medical University

摘　　要：目的　探讨老年恶性血液病患者医院感染的临床特点、发生原因及防治措施。方法　回顾分析 78例老年恶性血液病患者的院内感染发生率、危险因素、感染部位及治疗方法。结果　 78例中 42例 (5 3.8% )发生医院感染 ,高于同期非老年患者 (31 5 % )。危险因素为白细胞减少和化疗。感染部位以呼吸系统和口腔多见。感染病原菌主要为革兰阴性菌及真菌。结论　老年恶性血液病患者医院感染发生率高 ,疾病本身和化疗导致免疫抑制及骨髓抑制为医院感染的主要原因 。Objectives To investigate the clinical features,causes and treatment of the hospital infection in the elderly patients with hematological malignant diseases. Methods The nosocomically infective rate,the risk factors, the most commonly infected sites and therapeutic methods of 78 elderly patients were analyzed retrospectively.Results The incidence of nosocomial infection in the senile patients(53.8%) was higher than that of non-senile patients(31.5%) in the corresponding period.The high-risk factors included low WBC and chemotherapy.The most commonly infected sites were respiratory system and oral cavity.The common pathogenic bacteria were mainly Gram-negative bacteria and funguses. Conclusions The nosocomially infective incidence of elderly patients with hematological malignant diseases is higher.The main causes were ossium medulla and immune inhibition,primary diseases and chemotherapy. Experience antibiotic treatment and supportive therapy may be good to control infection.

关 键 词：恶性血液病 老年 医院感染 病原菌 危险因素 治疗 

分 类 号：R733[医药卫生—肿瘤] R181.34[医药卫生—临床医学]