人宫颈癌组织内脂质过氧化水平的测定  

Determination of Lipid Peroxidation in the Tissues of Human Uterine Cervix Carcinoma

作　　者：欧阳杰[1] 李文瑞[1] 武贵臻[1] 王月珠[2] 

机构地区：[1]新疆医学院生物化学教研室 [2]新疆医学院第一附属医院妇产科

出　　处：《新疆医学院学报》1991年第1期13-15,共3页

摘　　要：作者测定了人宫颈癌组织内脂质过氧化水平,并选择阴道尖锐湿疣和正常宫颈上皮组织作对照。宫颈癌、尖疣和正常组织内脂质过氧化产物丙二醛(MDA)含量分别为1.25±0.24(21)、0.80±0.35(15)和1.93±0.22nmol/mg·pro(15)。三组间经统计学处理的方差分析有显著性差异(P<0.0001),宫颈癌和尖疣内MDA含量均低于正常组织,有高度显著性差异(P<0.01)。结果提示脂质过氧化与细胞的增殖控制有关。Lipid peroxidation levels were determined in the tissues of human uterine cervix carcinoma compared with that of vaginal condyloma acuminatum and normal cervical epithelium. Contents of malonaldehyde (MDA) as a product of lipid peroxidation were 1.25±0.42, 0.80±0.35 and 1.93+0.22 nmol/mg. pro in cervical carcinoma,condyloma acuminatum and normal tissues respectively. The difference was highly significant among the three groups by analysis of variance(P<0.0001).MDAcontents were much lower in the former two tissues compared with normal ones(P<0.01).This indicates that lipid peroxidation may be related to hyperplasia control of cells.

关 键 词：宫颈癌 阴道 尖锐湿疣 脂质过氧化 

分 类 号：R737.330.2[医药卫生—肿瘤]