22例晚期膀胱癌患者术中放疗随访报告  

Intra operative radiation therapy for advanced bladder cancer (Report of 22 cases)

作　　者：金保庚[1] 李光[1] 向丛明[1] 陈平康[1] 陈葳[1] 沈德炘[1] 赵锡生[1] 

机构地区：[1]无锡市第四人民医院泌尿外科,江苏无锡214062

出　　处：《临床泌尿外科杂志》2002年第6期280-281,共2页Journal of Clinical Urology

摘　　要：目的:对晚期膀胱癌术中放疗患者进行临床效果观察,并与传统的全膀胱切除术进行比较,以探索一种更合理、有效的治疗晚期膀胱癌的途径。方法:术中将肿瘤处理完毕后,根据肿瘤情况,用直线加速器给予一次性剂量照射,作长期随访报告。结果:术中放疗后,膀胱内肿瘤局部复发低,本组仅有4例膀胱内小肿瘤复发,经TURBT治疗后未再复发。22例具有全膀胱切除指征的患者均保留了膀胱正常排尿功能,患者生活质量提高,生存期明显延长。结论:对位于膀胱三角区周围浸润型多发性膀胱癌,尤其是膀胱腺癌、鳞癌,可采用电子直线加速器进行术中放疗,是一种理想的治疗方法。Purpose:To report the therapeutic effects of patients with bladder cancer treated by intra operative radiation and to recommend an effective method for the treatment of advanced bladder cancer. Methods:During the operation, when the tumor of bladder had been removed, a boost dose of electric beam from a linear accelerator was irridiated to the tumor bed. 22 cases were followed-up in a 10 years period.Results: Lower local recurrence rate was observed in patients received intra-operative radiation therapy, only 4 cases had a small recurrent tumor in the bladder during the follow-up period. In the 22 cases with the indications for total cystectomy, the normal bladder function was preserved. The quality of life and the survival period improved.Conclusions:If the tumor was situated around the trigonal portion with invasive, multiple type, especially for adenocarcinoma or squamous cell carcinoma, total cystectomy or suprapubic cystostomy in the inoperable case was done in our hospital in the early period. Now we prefer the intra operative radiation therapy, because it is a suitable treatment for the advanced bladder cancer.

关 键 词：膀胱癌 直线加速器 放射治疗 

分 类 号：R737.140.5[医药卫生—肿瘤]