纤维源性肿瘤间质肥大细胞反应与预后的关系  

THE RELATIONSHIP BETWEEN PROGNOSIS AND MAST CELLS REACTION IN STROMA OF FIBROGENIC TUMOR

作　　者：杜华贞[1] 和瑞芝[1] 赵卫星[1] 千高峰[1] 何茶叶[1] 刘兴莉[2] 

机构地区：[1]新乡医学院病理教研室 [2]新乡市中心医院病理科

出　　处：《新乡医学院学报》1991年第4期261-263,共3页Journal of Xinxiang Medical University

摘　　要：本文对118例纤维源性肿瘤间质肥大细胞反应及预后进行了观察比较。其中纤维肉瘤33例,纤维瘤47例,瘤样纤维组织增生38例。瘤样纤维组织增生中间质肥大细胞数最多,纤维肉瘤间质肥大细胞较少,而纤维瘤间质肥大细胞数则位于两者之间。将术后随访五年的21例纤维肉瘤患者,按肿瘤间质肥大细胞数量的多少分为两组:(Ⅰ) 低计数组(≤2/HPF)、(2) 高计数组(>2/HPF)。结果显示:肥大细胞高计数组患者的五年生存率明显高于低计数组。故认为肿瘤间质肥大细胞反应是机体拮抗肿瘤的一种形态表现。The mast cells reaction and prognosis of patients were observed and compared in 118 patients with fibrogenic tumor. These cases included 33 cases of fibresarcoma, 47 cases of fibroma and 38 cases of fibromatoid hyperplasia. The number of mast cells in the stroma of the fibromatoid hyperplasia is the most, and the fewest is that of the fibrosarcoma, and that of the fibroma is moderate (P<0.001). The post-operative 21 cases with fibrosarcoma that were followed-up 5-year were divided into two groups according to the mast cells count in stroma of tumors (>2/HPF and ≤2/HPF). The result indicated that the cases with a high mast cell count show a significant better 5-year survival rate than those with a low count. Therefore, it is concluded that the reaction of mast cell in stroma of tumor is a behavior of host against tumor.

关 键 词：纤维源性肿瘤 肥大细胞 预后 

分 类 号：R730.262[医药卫生—肿瘤]