CA242生物半衰期监测大肠癌复发转移的评价  

Evaluation of biological half-life of CA242 in relapse or metastasis of colorectal carcinoma

作　　者：齐为民 张丽君[2] 朴东奎 

机构地区：[1]西安万杰医院实验诊断科,陕西西安710016 [2]第四军医大学唐都医院检验科,陕西西安710016 [3]第三军医大学检验系,重庆400038

出　　处：《免疫学杂志》2002年第B06期39-41,共3页Immunological Journal

摘　　要：目的　阐明CA2 4 2生物半衰期 (T1 2 )在大肠癌患者复发、转移中的意义。方法　CA2 4 2血清浓度采用单克隆抗体 (mAb)ABC ELISA两步法。结果　大肠癌患者CA2 4 2T1 2 >6d者 ,复发、转移的敏感性为 88.9% ,而单一CA2 4 2含量测定的敏感性仅为 33.3%。结论　CA2 4 2T1 2 预测大肠癌复发、转移的敏感性明显优于CA2 4 2含量测定 。Objective To evaluate the clinical value of biological half life of CA242 in relapse or metastasis of colorectal cancer. Methods Two steps' method of mAb sandwich ABC ELISA was used. Results When the time of biological half life of CA242 was more than six days, the sensitivity of relapse or metastasis was 88.9%,while serum CA242. It was only 33.3%,when serum CA242 was measured. Conclusion The sensitivity of biological half life of CA242 was better than its serum level in relapse or metastasis of colorectal cancer.

关 键 词：CA242 生物半衰期 监测 大肠癌 复发 肿瘤标志物 

分 类 号：R735.34[医药卫生—肿瘤]