氟西汀与阿米替林治疗老年抑郁症的疗效比较  

A comparison of therapeutic effects of fluoxetine and amitriptyline in the treatment of senile depression

作　　者：张玉海 赵燕[1] 王文安[2] 

机构地区：[1]泰安市复退军人精神病医院,271000 [2]泰安市精神卫生中心

出　　处：《山东精神医学》2002年第2期84-85,共2页Shangdong Archives of Psychiatry

摘　　要：目的 探讨氟西汀对老年抑郁症的临床疗效及副反应。方法 对80例老年抑郁症病人随机分为氟西汀组(40例)和阿米替林组(40例)进行治疗研究,采用HAMD、TESS量表分别评定疗效及副反应。结果 氟西汀与阿米替林对老年抑郁症的疗效相似,氟西汀副反应较阿米替林少而轻微。结论 氟西汀较适合于老年抑郁症的治疗,患者有较好的依从性。Objective To explore the efficacy and side effects of fluoxetine in the treatments of senile depression. Methods 80 patients were randomly assigned into fluoxetine group (n = 40) and amitriptyline group (n - 40) . The clinical efficacy was evaluated by HAMD. The side effects were evaluated by TESS. Results The efficacy of fluoxetine is similar to amitripytline in the treatment of senile depression. Howeer,fluoxetine had fewer side effects. Conclusion Fluoxetine appears to be more effective in treatment of senile depression and has good compliance.

关 键 词：氟西汀 阿米替林 老年抑郁症 治疗 疗效比较 

分 类 号：R749.405[医药卫生—神经病学与精神病学]