小儿恶性肿瘤住院化疗合并感染的临床分析  

Infectious Complications in Hospitalized Children with Malignancies during Chemotherapy: A Clinical Analysis

作　　者：卢新天[1] 叶中绿[2] 孙桂香[1] 朱英华[1] 华英[1] 李齐岳[1] 于载泺[1] 

机构地区：[1]北京大学第一医院,北京100034 [2]湛江医学院附属医院,广州湛江524001

出　　处：《中华医院感染学杂志》2002年第6期404-406,共3页Chinese Journal of Nosocomiology

摘　　要：目的　掌握小儿恶性肿瘤住院化疗过程中的感染状况。方法　对住院化疗的 96例肿瘤患儿的 74 2个疗程进行回顾性调查分析。结果　疗程的感染率为 2 1.4 % ;急性白血病诱导、巩固阶段的感染率分别为 5 0 .8%及4 3.9% ,高于治疗的其他阶段 ;73%的感染患儿血中性粒细胞 <10 0 0 / mm3。结论　小儿恶性肿瘤住院化疗合并感染与化疗的强度及血中性粒细胞数降低有关。OBJECTIVE To investigate infectious complications in childhood malignacies during chemotherapy in hospital. METHODS The 742 cycles of chemotherapy of 96 children with malignancies in our hematological ward were reviewed and analysed. RESULTS Infection rate of cycles was 21.4%. The infection rates of induction and consolidation periods were 50.8% and 43.9%, respectively, higher than other periods. There were 73% infectious episodes of which granulocyte counts were <1 000/mm 3. CONCLUSIONS The incidence of infectivity of children with malignancies during chemotherapy in hospital was related to intensity of chemotherapy and neutropenia.

关 键 词：临床分析 恶性肿瘤 獐寺 感染 粒细胞减少 

分 类 号：R730.26[医药卫生—肿瘤]