Ⅲ、Ⅳ期神经母细胞瘤治疗的临床体会  

Clinical Experience of Primary Tumor Bulkectomy in Advanced Neuroblastoma

作　　者：赵强[1] 张广超[1] 陈鸿骏[1] 闫杰[1] 李璋林[1] 曹嫣娜[1] 

机构地区：[1]天津医科大学附属肿瘤医院儿科,天津市300060

出　　处：《中国肿瘤临床》2002年第6期416-417,共2页Chinese Journal of Clinical Oncology

摘　　要：目的:讨论腹部进展期原发神经母细胞瘤(NB)减瘤术的临床体会。方法:对术前化疗后行原发肿瘤减瘤术的腹部进展期NB10例,与同期化疗后行原发肿瘤完整切除的腹部进展期NB24例进行临床对比分析。结果:行减瘤术组10例,1例生存41个月,1例生存11个月,8例死于诊断后1～10个月内,平均7个月。行完整切除组24例,18例生存18～59个月,平均25个月,其中3例36个月,1例59个月健在。Ⅲ期2例,Ⅳ期16例。结论:对腹部进展期NB的手术时机要有正确的判断,如术中考虑无法切除90%以上的原发灶,则应避免减瘤术。Objective:To study the clinical experience of primary tumor bulkectomy in advanced abdominal neuroblastoma.Methods:Thirty-four cases of advanced abdominal neurob-lastoma (including primary tumor bulkectomy 10cases and complete resection24cases)were ana-lyzed after preoperative chemotherapy.Results:Twenty four cases underwent completely resec-tioned,18of them had event-free interval for18～59months and the mean survival term was25month.Ten cases received primary tumor bulkectomy.Eight deaths occurred in1～10month and the mean survival term was7months.Conclusion:Bulkectomy could be unsuitable in ad-vanced abdominal neuroblastoma .

关 键 词：治疗 神经母细胞瘤 进展期 减瘤术 NB 儿童 临床分析 

分 类 号：R730.5[医药卫生—肿瘤]