子宫颈癌前和癌变患者血清标记物的研究  

A SURVEY OF TUMOR MARKERS IN PATIENTS WITH SQUAMOUS CELL CANCER AND PRECANCER OF UTERINE CERVIX

作　　者：谢汉华[1] 张志胜[1] 徐立礼[1] 

机构地区：[1]湖南医科大学第二附属医院妇产科

出　　处：《湖南医科大学学报》1989年第2期179-182,共4页Bulletin of Hunan Medical University

摘　　要：检测65例子宫颈癌前病变和癌变患者与102例正常对照组的SF、β-hCG、CEA、及AFP水平。结果实验组SF、β-hCG及CEA均显著高于对照组,并随子宫颈癌临床期别增高而升高;AFP在两组之间差异无显著性。SF、β-hCG及CEA诊断子宫颈癌的可用度分别为53.4％、55.7％、53.5％,三项指标联合应用的可用度可提高到70.0％。但无助于早期癌肿诊断。The circulating levels of serum ferritin ( SF) , beta-subunit human chorionic gonadotropin (β-hCG), carcinoembryonic antigen (CEA) and α-fetoprotein (AFP) in 65 patients and 102 healthy person as control were studied. The mean value of SF, β-hCG and CEA was significantly higher in patients than in control (P< 0.01), but there was no significant difference in AFP between these two groups ( P> 0.05) . The levels of SF, β-hCG and CEA rose as the stage of cervical cancer progresses.The availabilities of SF, β-hCG and CEA used in diagnosis of cervical cancer were 53.4%, 55.7% and 53.6% respectively, and was 70.0% when they were used in combination. However, they seem to be not helpful in the early diagnosis of cervical cancer.

关 键 词：宫颈癌 血清 标记物 鳞状细胞 

分 类 号：R737.6[医药卫生—肿瘤]