川续断的化学成分研究  

STUDIES ON THE CHEMICAL CONSTITUENTS OF DIPSACUS ASPER WALL.

作　　者：张永文[1] 薛智[1] 

机构地区：[1]中日友好临床医学研究所药物药理室

出　　处：《药学学报》1991年第9期676-681,共6页Acta Pharmaceutica Sinica

摘　　要：从川续断(Dosacus asper Wall)的根中分得六个化合物(Ⅰ～Ⅵ)。Ⅰ,Ⅱ,Ⅲ和Ⅵ分别鉴定为蔗糖、胡萝卜甙、β-谷甾醇和akebia saponin D.Ⅵ和Ⅴ为新化合物,根据光谱分析和化学方法证明其结构分别为3-O-(4-O-乙酰基)-α-L-吡喃阿拉伯糖常春藤皂甙元28-O-β-D-吡喃葡萄糖-(1→6)-β-D-吡喃葡萄糖酯甙和3-O-α-L-吡喃阿拉伯糖齐墩果酸28-O-β-D-吡喃葡萄糖-(1→6)-β-D一-吡喃葡萄糖酯甙。Six compounds Ⅰ～Ⅵ were isolated from the roots of Dipsacus asper Wall.. Compounds Ⅰ,Ⅱ, Ⅲ and Ⅵ were identified as sucrose, daucosterol, β-sitosterol and akebia saponin D, respectively. On the basis of spectral analysis and chemical evi-dence, the structures of two new compounds were established as 3- O- (4-O- acetyl)-α - L- arabinopyranosyl - hederagenin 28 - O - β - D- glucopyranosyl - (1→6 ) - β- D- glucopyranoside (Ⅳ) and 3 - O -α - L - arabinopyranosyl oleanolic acid 28 - O - β - D- glucopyranosyl - (1→6) -β - D - glucopyranoside (Ⅴ).

关 键 词：川续断 化学成分 三萜皂甙 

分 类 号：R284.1[医药卫生—中药学]